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Jianle Wang on Muck Rack

Jianle Wang

As seen in: Nature, Mondaq
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Articles

HDAC1 maintains metabolic homeostasis in nucleus pulposus cells via post-translational modification interactions with YBX1

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By Bohao Zhou, Jiechao Xia, Zhaowei Zhang, Bingbing Xu, Zixin Ruan, Fengjie Ma, Zhenlei Zhang, Teng Yao, Jun Gao, Jianle Wang, Zheyuan Zhang, Junxin Chen, Shiyuan Shi, Yongfeng Cui, Panyang Shen, Shuying Shen, Jianjun Ma, Tianyou Gao, Chen’an You
| Nature Verified
Abstract Intervertebral disc degeneration is characterized by the metabolic dysregulation of nucleus pulposus cells, which is regulated by complex post-translational modifications, manifesting as extracellular matrix remodeling and inflammatory microenvironment formation. We demonstrated the progressive downregulation of HDAC1 during disc degeneration. HDAC1 mediates the deacetylation and ubiquitination-dependent degradation of YBX1.
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FTC Weighs In On Orange Book Listing Of Drug-Device Patents - Patent - United States

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By Larissa C. Bergin, Patricia Campbell, Colleen Heisey, Jianle Wang
| Mondaq
In Short The Situation: On March 22, 2024, the Federal Trade Commission ("FTC") filed an amicus brief in Teva Branded Pharmaceutical Products R&D, et al. v. Amneal Pharmaceuticals of New York, LLC, et al., 2:23-cv-20964, U.S. District Court for the District of New Jersey ("Teva v.
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