Skip To Main Content
Shuying Shen on Muck Rack

Shuying Shen

As seen in: Nature, Annals of the Rheumatic Diseases
Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work. Claim your profile

Get in touch with Shuying

Contact Shuying, search articles and posts on X, monitor coverage, and track replies from one place.

Learn more about Muck Rack

Actions

Share this page

Is this you?

As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile

Articles

Chondrocytes reprogram chromatin in hypoxic microenvironments to activate CADM1-AS1/HDAC1 complex-mediated anti-inflammation signals

|
By Weiyu Ni, Tianyuan Gu, Panyang Shen, Zixuan Mei, Yizheng Wu, Nan Pan, Wentao Yang, Gang Liu, Yan Ma, Xiangqian Fang, Shunwu Fan, Haitao Zhang, Shuying Shen, Kamuran Yilamu
| Nature Verified
Abstract Maintaining chondrocyte homeostasis is crucial for the effective treatment of osteoarthritis. Chondrocytes reside in a hypoxic environment under physiological conditions. This study, conducted exclusively in male mice, examines the association between epigenetics and chondrocyte homeostasis and observes significant alterations in histone acetylation in chondrocytes under hypoxic conditions.
Open in Who Shared Issue with article?

Interleukin-16 enhances anti-tumor immune responses by establishing a Th1 cell-macrophage crosstalk through reprogramming glutamine metabolism in mice | Nature Communications

|
By tong liu, Yunkun Lu, Junjie Xu, Shuying Shen, Hui Li, Min Shang, Hongshan Guo, Qian Cao, Kai Wang, Wang Qingqing
| Nature Verified
Abstract Overcoming immunosuppression in the tumor microenvironment (TME) is crucial for developing novel cancer immunotherapies. Here, we report that IL-16 administration enhances the polarization of T helper 1 (Th1) cells by inhibiting glutamine catabolism through the downregulation of glutaminase in CD4+ T cells and increases the production of Th1 effector cytokine IFN-γ, thus improving anti-tumor immune responses.
Open in Who Shared Issue with article?

circPDE4B prevents articular cartilage degeneration and promotes repair by acting as a scaffold for RIC8A and MID1

|
By Shuying Shen, Yute Yang, Panyang Shen, Jun Ma
| Annals of the Rheumatic Diseases Verified
circPDE4B prevents articular cartilage degeneration and promotes repair by acting as a scaffold for RIC8A and MID1 Shuying Shen1,2, Yute Yang1,2, Panyang Shen1,2, Jun Ma1,2, Bin Fang3, Qingxin Wang4, Kefan Wang1,2, Peihua Shi1,2, http://orcid.org/0000-0002-8785-0280Shunwu Fan1,2, http://orcid.org/0000-0003-4500-8914Xiangqian Fang1,2 1 Department of Orthopaedic Surgery, Sir Run Run Shaw Hospital, Zhejiang University school of medicine, Hangzhou, China 2 Key Laboratory of Musculoskeletal System...
Open in Who Shared Issue with article?
See all 8 articles