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Jianxian Sun

As seen in: Environmental Health Perspectives, Nature, ACS Publications, BioRxiv, Cell Press, medRxiv
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Articles

Enantioselective protein affinity selection mass spectrometry (E-ASMS) - Nature Communications

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By Xiaoyun Wang, Jianxian Sun, Shabbir Ahmad, Conrad V. Simoben, Stuart Green Verified, Madhushika Silva, Elisa Gibson, Danai Mavridi, Christopher G. Lenz, Andreas C. Joerger, Wyatt W. Yue, Tyler S Beyett, Susanne Müller, Stefan Knapp, Dafydd Owen, Rachel Harding, Matthieu Schapira, Peter Brown, Vijayaratnam Santhakumar, Suzanne Ackloo, Cheryl H Arrowsmith, Aled Edwards, Hui Peng
| Nature Verified
Abstract We report an enantioselective protein affinity selection mass spectrometry screening approach (E-ASMS) that enables the detection of weak binders, informs on selectivity, and generates orthogonal confirmation of binding. After method development with control proteins, we screen 31 human proteins against a designed library of 8,217 chiral compounds.
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Enantioselective Protein Affinity Selection Mass Spectrometry (E-ASMS)

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By Xiaoyun Wang, Jianxian Sun, Shabbir Ahmad, Diwen Yang
| BioRxiv
Abstract We report an enantioselective protein affinity selection mass spectrometry screening approach (E-ASMS) that enables the detection of weak binders, informs about selectivity, and generates orthogonal confirmation of binding. After method development with control proteins, we screened 31 human proteins against a designed library of 8,210 chiral compounds.
Open in Who Shared Issue with article?

Synthesis and Toxicity Evaluation of p-Phenylenediamine-Quinones

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By Pranav Nair, Jianxian Sun, Linna Xie, Hannah Byun
| ACS Publications
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See all 13 licensed articles (14 Total)