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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
Sequence–activity mapping and model-guided engineering of the phenol-responsive DmpR–Po σ 54 promoter
Abstract Promoters are core cis-regulatory elements that determine gene expression levels and dynamic responses, and their quantitative engineering directly dictates the performance of synthetic biological systems such as whole-cell biosensors. However, the transcriptional output of complex inducible systems, exemplified by σ54-dependent promoters, relies on long-range coordination among distal bacterial enhancer-binding proteins, DNA architectural proteins, and RNA polymerase.
Nuclear Magnetic Resonance Fingerprinting and Principal Component Analysis Strategies Lead to Anti-Tuberculosis Natural Product Discovery from Actinomycetes
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