Jiaquan Lu

Keywords myelin evolutionary adaptation white matter injury oligodendrocyte Introduction The limited regenerative capacity of the central nervous system presents a major therapeutic challenge. This is particularly evident in disorders of the white matter, which is largely composed of myelinated axons and derives its function from the insulating myelin sheaths produced by oligodendrocytes.

Abstract Oxidative stress can be alleviated by antioxidants intakes. Taraxerol acetate (TA), a natural triterpenoid extracted from dandelions, may reduce the risk of metabolic disorders by regulating oxidative stress. In the study, we investigated the effects of TA in relieving oxidative stress in murine intestinal epithelial cells using multiomics techniques. Here, we found that TA activated the antioxidant defense system.