Jiawen Yin
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Synergistic effects of repetitive transcranial magnetic stimulation and a dance movement intervention on mild cognitive impairment: study protocol for a four-arm factorial randomized controlled trial
Abstract Background: Mild Cognitive Impairment (MCI) represents a critical transitional stage between normal cognitive aging and dementia, characterized by a high conversion rate to Alzheimer’s disease (AD). Current pharmacological interventions provide limited symptomatic relief and do not alter disease trajectory. Consequently, there is an urgent need for effective, multimodal, non-pharmacological interventions.
A patent review of GPR84 receptor antagonists (2020–present)
ABSTRACT Introduction GPR84 is a pro‑inflammatory, metabolite‑sensing Class A GPCR implicated in a range of inflammatory, fibrotic, metabolic, and neuropathic processes. Its inducible expression and role in amplifying innate immune responses have driven sustained interest in GPR84 antagonists as potential therapeutic agents.
Diastereoselective Formal [3+3] Cascade Cyclization towards Fused 4‐Fluoroalkylated 3,4‐Dihydro‐2H‐pyrans via Copper Catalysis
Supporting Information Filename Description cjoc202500157-sup-0001-supinfo.pdfPDF document, 18.4 MB Appendix S1: Supporting Information References 1For selected exemples, see: (a) ; ; ; ; A comprehensive review on β-lapachone: Mechanisms, structural modifications, and therapeutic potentials. Eur. J. Med. Chem. 2021, 210, 112962; (b) ; ; ; Unusual Nitrogenous Derivatives from Alstonia. Nat. Prod. Commun.
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