Jiaying Mo
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Inhibition of ferroptosis improves developmental competence of vitrified–warmed oocytes
Abstract Background: Oocyte vitrification is widely used for female fertility preservation. However, current vitrification procedures can compromise oocyte quality, leading to increased oxidative stress and organelle dysfunction. Therefore, optimizing vitrification strategies to improve oocyte developmental competence is essential. Methods: Mouse oocytes were randomly assigned to control (CON) and vitrification (VIT) groups.
Multi‐Omics Revealed the Effects of Intrauterine Hyperglycemia Exposure on the Development of Skeletal Muscle in Offspring
1 Introduction Gestational diabetes mellitus (GDM) traditionally referred to the first occurrence of abnormal maternal glucose metabolism during pregnancy, which was one of the common complications during pregnancy [1]. A growing number of studies found that maternal hyperglycemia was closely related to the occurrence of obesity, abnormal glucose and lipid metabolism, hypertension, depression and other diseases in the offspring at their adulthood [2-7].
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