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Jiejunyi Liang

As seen in: Nature
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Articles

Intestinal stem cells count self-renewal divisions to switch multipotency

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By Dong Tong, Anqi Li, Quanquan Jiang, Xiaozhao Liu, Ximiao HE, Jiejunyi Liang, Yunyun Han, Zheng Guo, Qili Yuan
| Nature Verified
Abstract Multipotent stem cells maintain tissue homeostasis by producing distinct daughter cell types in defined proportions1,2, but how they coordinate type-specific ratios during repeated divisions remains unknown. Drosophila intestinal stem cells (ISCs) switch between producing enteroendocrine cells (EECs) and enterocytes (ECs)3,4, yet maintain a constant EEC:EC ratio despite rapid tissue turnover5,6,7.
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Anterior cingulate cortex provides the neural substrates for feedback-driven iteration of decision and value representation - Nature Communications

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By Jiejunyi Liang
| Nature Verified
Abstract Adjusting decision-making under uncertain and dynamic situations is the hallmark of intelligence. It requires a system capable of converting feedback information to renew the internal value. The anterior cingulate cortex (ACC) involves in error and reward events that prompt switching or maintenance of current decision strategies.
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