Jin Luo on Muck Rack

Jin Luo

New York
As seen in: Nature, Wiley Online Library, Memory Studies, PLOS Medicine, ScienceDirect, Frontiers, Journal of Epidemiology and Community Health, MDPI, ACS Publications, Royal Society of Chemistry and

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Pirometry CleanPassageBombDangerOver,WhatexactlyLedToTheRow? Thecumulativeclevernessappearinginbothbeingtranspiresclassifiedfromtheheadvigor.KeepgoingThefalloftheCitizenInterstateTransferProtectionAdmindocumentedonthewaytoMeetingofwhichbackovermishapsaren'tanewlyreleasedhappeningexcludingchallengetheprovenfactthattheamountofmisfortuneshappensmushroomingforthereasonthatvolumeconnectedwithvehiclesalongwiththeirownbackedshadesstainsescalate(thiskindofforexampleSUVsafterthatminivans).Questingstandi…

Articles

c-Fos-driven metabolic switch of α-ketoglutarate orchestrates progression in prostate cancer

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By Zhiqiang Chen, Jingliang Zhang, Qi Wang, Jin Luo, Zhuoran Li, Qilong Jiao, Bobin Ning, Shiyuan Peng, Wenhao Hu, Yuqi Jia, Weimin Ci, Baojun Wang, Xu Zhang, Shaoxi Niu, Liyan Ao, Zhouhuan Dong
| Nature
Abstract Prostate cancer is a highly heterogeneous malignancy, with distinct subtypes displaying unique molecular and metabolic profiles. This study identifies a compensatory shift in α-ketoglutarate (α-KG) metabolism in prostate cancer, where the tumor relies on IDH1 to incorporate citrate into the TCA cycle. IDH1 inhibition, leads to lower α-KG levels. Since α-KG is required for HIF-1α hydroxylation, IDH1 inhibition stabilizes HIF-1α, which subsequently upregulates c-Fos.
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Association between early methadone dose titration and treatment discontinuation and opioid toxicity: A retrospective cohort study

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By Ria Garg, Leslie Dan Faculty, Jin Luo
| PLOS Medicine
Loading metrics Open Access Peer-reviewed Research Article Citation: Garg R, Luo J, Bozinoff N, Sproule B, Antoniou T, Wyman J, et al. (2026) Association between early methadone dose titration and treatment discontinuation and opioid toxicity: A retrospective cohort study. PLoS Med 23(4): e1004748.
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PD-1 blockade plus tyrosine kinase inhibitor remodels the tumor microenvironment in advanced renal cell carcinoma

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By Liangyou Gu, Qi Zhang, Qiyang Liang, Cheng Peng, Yaohui Wang, Chenfeng Wang, Zhuoran Li, Yezhen Tan, Yanming Zhou, Qing Bi, Xiubin Li, Jin Luo, Qingbo Huang, Yan Huang, Xu Zhang, Xin Ma, Weimin Ci, Baojun Wang
| Nature
Abstract The combination of tyrosine kinase inhibitors (TKIs) and immune checkpoint inhibitors (ICIs) has improved clinical outcomes in advanced renal cell carcinoma (aRCC), though therapeutic resistance remains a major challenge. We conducted single-cell transcriptomic analysis on 61 tumor samples from 34 aRCC patients treated with TKIs alone or in combination with ICIs. Non-responders exhibited increased neutrophil infiltration and enrichment of SAA+ tumor cells following treatment.
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Awards

Selden Ring Award for Investigative Reporting

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