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Articles by Jing Pu
Safety and immunogenicity of inactivated human Rotavirus vaccine in young children and infants: a randomized, placebo-controlled, double-blind, phase I clinical trial
Abstract Inactivated rotavirus vaccines (IRV) are an effective approach for providing protection against the virus. This double-blind, randomised, placebo-controlled, dose-escalation phase I trial evaluated the safety and immunogenicity of IRV in 288 healthy children aged 2–71 months without prior rotavirus vaccination or HIV infection.
Multi-omics reveals mechanism of combined L-cysteine and GABA in loquat postharvest quality
Abstract Loquat is highly susceptible to postharvest deterioration, including browning and lignification, which limits its storage life. This study investigated the effects of combined L-cysteine (L-Cys) and γ-aminobutyric acid (GABA) treatment on postharvest quality maintenance of loquat fruit and elucidated the underlying molecular mechanisms through integrated transcriptomic and metabolomic analyses.
Development and evaluation of a multiplex PCR-based dual-platform targeted sequencing framework for precise differentiation of lumpy skin disease virus
Abstract Background: Lumpy skin disease virus (LSDV) shares over 96% genomic identity with goatpox and sheeppox viruses, presenting severe diagnostic challenges due to cross-reactivity. Methods: To address this bottleneck, we established a targeted sequencing framework integrating multiplex PCR with short-read and long-read platforms.
SARS-CoV-2 ORF3a blocks lysosomal cholesterol egress by disrupting VPS39-regulated NPC2 trafficking and BMP metabolism
Keywords cellular cholesterol transport HOPS retromer bis(monoacylglycero)phosphates BMPs lysosome-mitochondrion interactions Research topic(s) CP: microbiology CP: cell biology Introduction Cholesterol plays a vital role in maintaining cellular structure and functions. Thus, cells tightly regulate cholesterol levels and distribution through multiple pathways. Cholesterol pathways are not only disturbed in metabolic disorders but also hijacked in infectious diseases.
Lycium barbarum polysaccharides enhance testicular spermatogenesis in d‐galactose‐induced aging rats via calcium signaling
1 INTRODUCTION Aging is an inevitable process characterized by a gradual decline in physiological functions, leading to increased susceptibility to diseases and organ failure.
Study on Slagging Mechanism of Heating Surface in CFB Boiler with Mixed Biomass Fuel
The slagging behavior was investigated in a 75 t·h−1 biomass circulating fluidized bed (CFB) boiler using a fuel mix composed of five biomass types: eucalyptus bark, wood tailings, industrial composite board, bamboo, and wood board. Severe superheater slagging highlights the need to investigate slagging mechanisms in mixed biomass fuels, considering the characteristics of multiple feedstocks.
Investigation on the Natural Convection Inside Thermal Corridors of Industrial Buildings
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Effects of L-Cysteine and γ-Aminobutyric Acid Treatment on Postharvest Quality and Antioxidant Activity of Loquat Fruit during Storage
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by Huifen Zhang †, Jing Pu †, Han Liu , Miao Wang , Ying Du , Xiaofu Tang , Xian Luo , Yongqing Wang and Qunxian Deng * College of Horticulture, Sichuan Agricultural University, Chengdu 611130, China * Author to whom correspondence should be addressed. † These authors contributed equally to this work. Int. J. Mol. Sci.
The Effect of State Ownership on a Cross-Border Acquisition Wave
1. Introduction Acquisitions generally occur in a pattern of waves—short periods of intense merger activity in an industry []. Prior studies have shown that the position of the merger and acquisitions (M&A) wave affects the acquiring firms’ performance [] and profits. Over the past decades, most of the growth in international production has been achieved through cross-border acquisitions(CBA) []. However, scholars also have examined waves in domestic M&A in industries [].
Exploring the Driving Factors and Their Spatial Effects on Carbon Emissions in the Building Sector
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Development of a mechanism for reconstruction of terahertz single-frequency images of biological samples
Abstract Algorithmic mechanisms are used to improve terahertz (THz) image quality, which is critical to a biological sample analysis. A complete mechanism for the super-resolution reconstruction and evaluation of THz biological sample images was constructed in this study.
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