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Jing-Ying Yu on Muck Rack

Jing-Ying Yu

As seen in: Cell Press
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Articles

Suppressed Calbindin Levels in Hippocampal Excitatory Neurons Mediate Stress-Induced Memory Loss

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By Ji-Tao Li, Xiao-Meng Xie, Jing-Ying Yu, Ya-Xin Sun
| Cell Press Verified
Calbindin Knockdown in Both CA1 and DG Neurons Mimicked Early-Life Stress-Induced Spatial Memory Loss Calbindin Knockdown in CA1 Excitatory, but Not Inhibitory, Neurons Impaired Spatial Memory The CRHR1-Nectin3 Pathway Mediates the Downregulation of Hippocampal Calbindin Levels by Early-Life Stress To investigate the role of hippocampal calbindin in spatial memory, we first injected AAV-shCalb1 into the DG and CA1 of adult C57BL/6N mice to knock down calbindin levels in both regions...
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