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J.N.W.B. Barker on Muck Rack

J.N.W.B. Barker

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Secukinumab for patients failing previous tumour necrosis factor‐α inhibitor therapy: results of a randomized open‐label study (SIGNATURE)

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By R.B. Warren, A.Y. Finlay, A.D. Burden, J.N.W.B. Barker
| Wiley
Biological therapy, particularly with tumour necrosis factor (TNF)‐α inhibitors, has revolutionized the treatment of moderate‐to‐severe chronic plaque psoriasis. However, it does not fully meet patients’ needs. Some patients fail to respond or lose response over time1, 2 and treatment strategies for these patients are unclear.
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