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Jocelyn G. Labombarde on Muck Rack

Jocelyn G. Labombarde

As seen in: Cell Reports, American Society for Microbiology (ASM)
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Articles

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By Jocelyn G. Labombarde, Marie Wehenkel, Chun-Yang Lin, Meenu R. Pillai, Rachael Keating, Scott Brown, Jeremy Crawford, David C. Brice, Clifford S Guy, Juan Mejia
| Cell Reports Verified
Highlights • Human and mouse broadly reactive influenza antibodies bind self-antigens • Enhancing broadly reactive antibodies exacerbates disease in models of autoimmunity • Transfer of broadly reactive monoclonal antibodies augments autoimmune disease • Humans infected with novel influenza subtypes have elevated autoreactive antibodies Summary Infection and vaccination repeatedly expose individuals to antigens that are conserved between influenza virus subtypes.
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Broadly Reactive Influenza Antibodies Are Not Limited by Germinal Center Competition with High-Affinity Antibodies

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By Rachael Keating, Jenny Johnson, David C. Brice, Jocelyn G. Labombarde
| American Society for Microbiology (ASM)
Research Article | Host-Microbe Biology Rachael Keating, Jenny L. Johnson, David C. Brice, Jocelyn G. Labombarde, Alexander L. Dent, Maureen A. McGargill Thomas E. Morrison, Editor DOI: 10.1128/mBio.01859-20 ABSTRACT Enhancing the generation of broadly reactive antibodies against influenza A virus (IAV) is a pertinent goal toward developing a universal IAV vaccine.
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