Johan Ormel
Netherlands
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Articles by Johan Ormel
Genetic insights into resting heart rate and its role in cardiovascular disease - Nature Communications
Method details Populations The full RHR meta-analysis included 100 studies with data on RHR in up to 835,465 individuals. RHR was obtained from ECG in 54 studies, from pulse rate in 31 studies (of which seven were self-measured by the participants), from blood pressure monitor in nine studies, from electronic medical records in three studies, from manual measurement in one study and through a combination of multiple of the before mentioned methods in two studies.
Annual Research Review: Stability of psychopathology: lessons learned from longitudinal population surveys
Introduction Psychopathology has been long recognized as a fluctuating process with various expressions over time, which can only be properly understood if we follow individuals and their social context from childhood up until adulthood. Luckily enough, several research groups throughout the world have invested the substantial means and efforts required to set up such longitudinal epidemiological surveys over the past decades.
Debate: Giving prevention a chance to prove its worth in lowering common mental disorder prevalence: how long will it take?
Abstract Large increases in treatment of Common Mental Disorders (CMD) have failed to reduce population prevalence and global burden. Preventive strategies are needed to lower CMD prevalence and burden.
Reducing Common Mental Disorder Prevalence in Populations
The burden of common mental disorders (CMDs), including major depressive and anxiety disorders, is substantial. CMDs contribute to lowered work productivity, family dysfunction, substance misuse, suicide, and reduced life expectancy.
Prevention of depression will only succeed when it is structurally embedded and targets big determinants
Letter to the Editor Prevention of depression will only succeed when it is structurally embedded and targets big determinants About 150 million people worldwide are affected with major depressive disorder (further depression) at any moment, and one in every five women and one in every eight men experience an episode of major depression over the course of their life.
Prefrontal cortex activation during a cognitive reappraisal task is associated with real-life negative affect reactivity
The neural substrate of cognitive reappraisal has been well-mapped. Individuals who successfully downregulate negative affect (NA) by reshaping their thoughts about a potentially emotional situation show augmented activity in the prefrontal cortex (PFC), with attenuated activity in the amygdala. We performed functional neuroimaging with experience sampling to determine whether individual differences in brain activation correspond to differences in real-life NA.
Filling the Gap
Author Contributions A. Aleman, J. Ormel, M. N. Servaas, and H. Riese developed the study design. M. N. Servaas collected the data. I. M. Nolte and H. Riese supervised genotype assessment. J. A. Bastiaansen performed statistical data analysis under the supervision of J. B. C. Marsman and A. Aleman. J. A. Bastiaansen drafted the manuscript, and all authors provided critical revisions and approved the final version of the manuscript for submission.
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