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EZH2 inhibition enhances T cell immunotherapies by inducing lymphoma immunogenicity and improving T cell function

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By Yusuke Isshiki, Xi Chen, Matt Teater, Ioannis Karagiannidis, Winson Cai, Cem Meydan, Min Xia, Hao Shen, Johana Gutierrez, Vigneshwari Easwar Kumar, Sebastian Carrasco, Madhu M. Ouseph, Samuel Yamshon, Peter Martin, Ofir Griess, Efrat Shema, Patrizia Porazzi, Marco Ruella, Renier J Brentjens, Giorgio G. Inghirami, Roberta Zappasodi, Amy Chadburn, Ari M Melnick, Wendy Béguelin
| Cell Press Verified
Keywords EZH2 T cell immunotherapy CAR-T bispecific antibodies follicular lymphoma DLBCL Get full text access Log in, subscribe or purchase for full access. References 1. Schuster, S.J. ∙ Svoboda, J. ∙ Chong, E.A. ... Chimeric Antigen Receptor T Cells in Refractory B-Cell Lymphomas N. Engl. J. Med. 2017; 377:2545-2554 2. Locke, F.L. ∙ Miklos, D.B. ∙ Jacobson, C.A. ... Axicabtagene Ciloleucel as Second-Line Therapy for Large B-Cell Lymphoma N. Engl. J. Med. 2022; 386:640-654 3. Bishop, M.R. ∙ Dickinson, M.
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