I certainly have concerns about any new treatment. My approach to any medication is to understand first on paper how it works: what’s the physiology, the mechanism, what is the science behind it? Then we really need to look at the harms, and have good clinical trials, to understand not only if it will work but also if it will be safe. So, my concerns with any new medication are what its safety profile is and if it will work the way we expect it to.