Jordi Barretina

Abstract Understanding the process of adaptation remains a key challenge for strength and conditioning coaches to enhance basketball athletic performance. While physical performance improvements are often used to track progress, these changes originate from various molecular mechanisms, with DNA methylation potentially playing a pivotal role in training-induced adaptations.

The Supplementary Information of our original Letter ( https://doi.org/10.1038/nature11003 ) and the Addendum published on 28 November 2012 ( https://doi.org/10.1038/nature11735 ; hereafter referred to as ‘first Addendum’) contain all of the data used for our analyses. These data include normalized activity (growth inhibition) responses for every cell line at each dose for all 24 of the compounds and drugs tested.