Jörg Tost on Muck Rack

Jörg Tost

France
As seen in: Environmental Health Perspectives, Nature, Wiley Online Library, Frontiers, MDPI, The Lancet, Epigenomics, Future Medicine, The Journal of Allergy & Clinical Immunology, TechTrends
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Articles

Imputation strategy for population DNA methylation sequencing data

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By Abel Garnier, Jörg Tost, Alexandre Duplan, Shannon Brandt
| biorxiv.org
Abstract Motivation: DNA methylation plays a crucial role in gene regulation and epigenetic inheritance, making it essential information for studies of genotype-environment interactions. As whole genome sequencing for DNA methylation analysis is still expensive at the population level, studies focus on regions of interest. However, data matrices may contain missing data for some individuals, which can hamper analyses.
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Epigenome-Wide Associations of Placental DNA Methylation and Behavioral and Emotional Difficulties in Children at 3 Years of Age

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By Aurelie Nakamura, Jörg Tost, Daniel Vaiman, Lucile Broséus
| MDPI
Abstract : The placenta is a key organ for fetal and brain development. Its epigenome can be regarded as a biochemical record of the prenatal environment and a potential mechanism of its association with the future health of the fetus. We investigated associations between placental DNA methylation levels and child behavioral and emotional difficulties, assessed at 3 years of age using the Strengths and Difficulties Questionnaire (SDQ) in 441 mother–child dyads from the EDEN cohort.
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Do not be scared of the genome's 5th base-Explaining phenotypic variability and evolutionary dynamics through DNA methylation analysis

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By Jörg Tost
| ncbi.nlm.nih.gov
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