Skip to main content
Jorge D. Calderin on Muck Rack

Jorge D. Calderin

As seen in: PNAS, BioRxiv
Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work. Claim your profile

Get in touch with Jorge D.

Contact Jorge D., search articles and posts on X, monitor coverage, and track replies from one place.

Learn more about Muck Rack

Actions

Share this page

Is this you?

As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile

Articles

Lysophospholipid headgroup size, and acyl chain length and saturation differentially affect vacuole acidification, Ca2+ transport, and fusion

|
By Chi Zhang, Yilin Feng, Jorge D. Calderin, Adam Balutowski
| BioRxiv
Abstract SNARE-mediated membrane fusion is regulated by the lipid composition of the engaged bilayers. Lipid composition impacts fusion through direct protein lipid interactions or through modulating the physical properties of membranes at the site of contact, including the induction of positive curvature by lysophospholipids (LPLs). The degree of positive curvature induced is due to the length and saturation of the single acyl chain in addition to the size of the head group.
Open in Who Shared Issue with article?

Sphingolipids regulate the tethering stage of vacuole fusion by affecting membrane fluidity

|
By Chi Zhang, Logan R. Hurst, Jorge D. Calderin, Zeynep D Gokbayrak
| BioRxiv
Abstract Sphingolipids are essential in membrane trafficking and cellular homeostasis. Here, we show that sphingolipids containing very long-chain fatty acids (VLCFAs) promote robust homotypic vacuolar fusion in Saccharomyces cerevisiae. The elongase Elo3 adds two carbons to 24-carbon (C24) fatty acids to make C26 VLCFAs that are incorporated into sphingolipids. Vacuoles isolated from elo3Δ cells had increased fluidity relative to the wild-type (WT) and were attenuated for fusion.
Open in Who Shared Issue with article?

Anionic nanoparticle-induced perturbation to phospholipid membranes affects ion channel function

|
By Isabel U. Foreman-Ortiz, Dongyue Liang, Elizabeth D. Laudadio, Jorge D. Calderin
| PNAS Verified
Anionic nanoparticle-induced perturbation to phospholipid membranes affects ion channel function Isabel U. Foreman-Ortiz, Dongyue Liang, Elizabeth D. Laudadio, Jorge D. Calderin, Meng Wu, Puspam Keshri, Xianzhi Zhang, Michael P. Schwartz, Robert J. Hamers, Vincent M. Rotello, Catherine J. Murphy, Qiang Cui, Joel A. Pedersen Proceedings of the National Academy of Sciences Oct 2020, 202004736; DOI: 10.1073/pnas.2004736117
Open in Who Shared Issue with article?
See all 3 articles