Jose Carlo Sosa on Muck Rack

Jose Carlo Sosa

As seen in: The Journal of Biological Chemistry
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Articles

Inflammation-induced iron transport and metabolism by brain microglia

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By Ryan McCarthy, Jose Carlo Sosa, Andrew M. Gardeck, Andrew S. Baez
| The Journal of Biological Chemistry Verified
Microglia are immune cells of the central nervous system and are implicated in brain inflammation. However, how brain microglia modulate transport and metabolism of the essential metal iron in response to pro- and anti-inflammatory environmental cues is unclear. Here, we characterized uptake of transferrin (Tf)-bound iron (TBI) and non-Tf–bound iron (NTBI) by immortalized microglial (IMG) cells.
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Inflammation-induced Iron Transport and Metabolism by Brain Microglia

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By Ryan McCarthy, Jose Carlo Sosa, Andrew M. Gardeck, Andrew S. Baez
| The Journal of Biological Chemistry Verified
Microglia are immune cells of the central nervous system and are implicated in brain inflammation. However, how brain microglia modulate transport and metabolism of the essential metal iron in response to pro- and anti-inflammatory environmental cues is unclear. Here, we characterized uptake of transferrin (Tf)-bound iron (TBI) and non-Tf–bound iron (NTBI) by immortalized microglial (IMG) cells.
Open in Who Shared Issue with article?
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