Colorectal cancer is the 2nd most frequently occurring cancer for men and women for the period 2018-2022, according to the Singapore Cancer Registry Annual Report 2022. This cancer is the second most common cause of death in cancer patients. Understanding the costs associated with its treatment is crucial for patients and their families. This article will explore the various expenses involved in colorectal cancer treatment, including colonoscopy screening, surgery, chemotherapy, and radiotherapy.