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Articles by Jun Chu
Caregiving across the lifespan: examining associations between loneliness and caregiver support services across life-course positions
Abstract Objectives This study examined whether formal caregiving support utilization (caregiver respite and support groups) varies across the life course and whether associations between support use and caregiver loneliness differ by age. Methods Data were drawn from four pooled waves (2011, 2015, 2017, and 2021) of the National Study of Caregiving linked to the National Health and Aging Trends Study (N = 5,530 caregiver observations).
Using Social Determinants of Health ICD-10 Z-codes to Identify Non-Medical Factors among Asthma Hospitalizations in the United States, 2016-2022
The authors have declared no competing interest. I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.
Associations of childhood-to-adulthood body size trajectories with dementia risk and brain structural imaging markers: a study from UK Biobank
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Abstract Background: Childhood and adulthood adiposity may influence dementia risk and brain structure; however, their life-course interplay and potential sex-specific effects remain incompletely understood. Methods: We analyzed 488,397 UK Biobank participants with self-reported comparative body size at age 10 (categorized as thinner, average, or plumper relative to peers) and measured adulthood BMI, followed prospectively for incident dementia.
By Zihang Zhang, Pan Zhang, Yanyan Li Verified, Jun Chu, Chengwei Su, Zhixin Hu, Houren Xiong, Gongxia Xu
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Frontiers
A Small-Molecule Naphthoquinone-Based Organic Cathode Material for High-Performance Lithium-Ion Batteries Click to copy article link Article link copied!
Cite Jump to ExpandCollapse ArticleMay 26, 2026 A Small-Molecule Naphthoquinone-Based Organic Cathode Material for High-Performance Lithium-Ion Batteries Click to copy article linkArticle link copied! Fang Xiao Fang Xiao College of Materials Science and Engineering, Changsha University of Science and Technology, Changsha, Hunan Province 410114, China College of Chemistry and Molecular Sciences, Hubei Key Laboratory of Electrochemical Power Sources, Wuhan University, Wuhan, Hubei Province...
A highly sensitive genetically encoded red cAMP sensor for multiplex imaging in vivo
Abstract Circularly permuted green fluorescent protein (cpGFP)-based high-performance cAMP sensors have enabled real-time monitoring of cAMP dynamics with high spatiotemporal resolution in living animals. However, their utility is hampered by significant spectral overlap with other green/yellow fluorescent indicators and blue/cyan light-activated optogenetic actuators, limiting their compatibility in multiplexed imaging applications.
Modelling the city choices of real estate developers in China
Real estate developers act as “city builders”, significantly driving urban and regional development. However, there has been a notable lack of quantitative analysis exploring how these developers make location choices among different cities, particularly in relation to formal and informal institutions. Grounded in the framework of “new institutionalism,” this paper models the city choice processes employed by real estate developers.
A bone-derived hormone permits rapid visual escape via GPR37 receptor in a subpopulation of VTA GABAergic neurons
Main text (Neuron 114, ◼◼◼–◼◼◼; May 6, 2026) In the originally published online version of this article, several errors appeared in the text and figures. In Figure 1D, two panels were inadvertently duplicated. In Figure 1H, the second bar was inadvertently duplicated in two plots. In Figure S1, panel A was inadvertently omitted from the supplemental file.
A bone-derived hormone permits rapid visual escape via GPR37 receptor in a subpopulation of VTA GABAergic neurons
Keywords visual escape bone-derived hormone osteocalcin GPR37 ventral tegmental area THIK-1 channel Get full text access Log in, subscribe or purchase for full access. References 1. Romer, A.S. (1933). Eurypterid Influence on Vertebrate History. https://doi.org/10.1038/s41583-023-00736-3. 2. Tseng, Y.-T. ∙ Schaefke, B. ∙ Wei, P. ... Defensive responses: behaviour, the brain and the body Nat. Rev. Neurosci. 2023; 24:655-671 3. LeDoux, J. Rethinking the emotional brain Neuron. 2012; 73:653-676 4. LeDoux, J.
Multifunctional Cellulose Derivative Enables Efficient and Stable Wide‐Bandgap Perovskite Solar Cells by Inhibiting Ion Migration
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions. Supporting Information Filename Description smll72276-sup-0001-SuppMat.docx2.7 MB Supporting File: smll72276-sup-0001-SuppMat.docx.
Assess Reproductive Health in SLE Clinic Visits
SLE predominantly affects women of childbearing age. Women affected by SLE have a higher risk for infertility, miscarriages, and other pregnancy complications due to disease activity, renal involvement, medications, and presence of certain autoantibodies.
Does Early Life Adversity Limit Delivery of High‐Quality Health Care Among Children?
Adverse childhood experiences (ACEs) are a pressing population health concern. While children with a history of ACEs have more health concerns, they are less likely to use certain kinds of health care. This study showed that children with a history of ACEs are less likely to receive care that involved shared-decision making, an indicator of high-quality health care. Providers and health care administrators should increase efforts to ensure that vulnerable children receive high quality health care.
Quantifying second-messenger information transmission in bacteria - Nature Physics
Abstract Bacterial second messengers are crucial for transmitting environmental information to cells. However, quantifying their information transmission capacity remains challenging. Here we develop a framework for quantifying information processing in cellular signalling systems. We engineer an isolated cyclic adenosine monophosphate (cAMP) signalling channel in Pseudomonas aeruginosa using targeted gene knockouts, optogenetics and a fluorescent cAMP probe.
Primary ciliary protein kinase A activity in the prefrontal cortex modulates stress in mice
Keywords primary cilium animal stress prefrontal cortex excitatory neuron corticosterone PKA activity Get full text access Log in, subscribe or purchase for full access. References 1. de Kloet, E.R. ∙ Joëls, M. ∙ Holsboer, F. Stress and the brain:: From adaptation to disease Nat. Rev. Neurosci. 2005; 6:463-475 2. McEwen, B.S. Physiology and neurobiology of stress and adaptation: Central role of the brain Physiol. Rev. 2007; 87:873-904 3. Lupien, S.J. ∙ McEwen, B.S. ∙ Gunnar, M.R. ...
Marek’s disease virus-1 unique gene LORF1 is involved in viral replication and MDV-1/Md5-induced atrophy of the bursa of Fabricius
Loading metrics Open Access Peer-reviewed Research Article Citation: Bao C, Chu J, Gao Q, Yang S, Gao X, Chen W, et al. (2025) Marek’s disease virus-1 unique gene LORF1 is involved in viral replication and MDV-1/Md5-induced atrophy of the bursa of Fabricius. PLoS Pathog 21(2): e1012891.
Comprehensive treatment of Anaplastic thyroid cancer: a case report
Back to Journals » OncoTargets and Therapy » Volume 18 Authors Liu J, Chu J Received 2 November 2024 Accepted for publication 25 February 2025 Published 10 March 2025 Volume 2025:18 Pages 325—333 DOI https://doi.org/10.2147/OTT.S504279 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Dr John Maher JiaQi Liu, Jun Chu Breast and Thyroid Surgery Department, Zibo Central Hospital, Zibo, Shandong Province, People’s Republic...
Factorial and Criterion Validities of the Chinese Version of Rosenberg
Back to Journals » Psychology Research and Behavior Management » Volume 17 Authors Peng W, Zhou Y, Chu J, Liu Z, Zheng K, Yao S, Yi J Received 3 September 2024 Accepted for publication 21 November 2024 Published 5 December 2024 Volume 2024:17 Pages 4135—4144 DOI https://doi.org/10.2147/PRBM.S494452 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Dr Gabriela Topa Wanrong Peng,1,* You Zhou,1,2,* Jun Chu,1...
Materials | Free Full-Text | Effects of Pyrolysis Temperature and Acid-Base Pre-Treatment on the Synthesis of Biochar-Based Slow-Release Selenium Fertilizer and Its Release in Soil
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Cost-Effective Rechargeable Magnesium Battery Based on a Fluorinated Alkoxyaluminate Electrolyte and a Carbonyl Polymer Cathode
RETURN TO ARTICLES ASAPPREVEnergy, Environmenta...Energy, Environmental, and Catalysis ApplicationsNEXT Zijun Hu Hubei Key Lab of Electrochemical Power Sources, College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China , Liang Huang Hubei Key Lab of Electrochemical Power Sources, College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China , Xiaotang Gan Hubei Key Lab of Electrochemical Power Sources, College of Chemistry and Molecular Sciences,...
Correspondence on ‘Clinical course of coronavirus disease 2019 (COVID-19) in a series of 17 patients with systemic lupus erythematosus under long-term treatment with hydroxychloroquine’
Correspondence on ‘Clinical course of coronavirus disease 2019 (COVID-19) in a series of 17 patients with systemic lupus erythematosus under long-term treatment with hydroxychloroquine’ Free Statistics from Altmetric.com Request Permissions If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.
School-Based Health Centers, Access to Care, and Income-Based Disparities
Key Points Question What is the association between school-based health centers and access, use, and health among children from low-income families?
Application of CERQ in Chinese community elderly
Back to Journals » Psychology Research and Behavior Management » Volume 16 Authors Ding Z, Song Q, Chu J, Zou T, Zheng K, Liu Z, Peng W, Yi J Received 12 December 2022 Accepted for publication 4 March 2023 Published 15 March 2023 Volume 2023:16 Pages 829—839 DOI https://doi.org/10.2147/PRBM.S401087 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Professor Mei-Chun Cheung Zixia Ding,1,2,* Qian Song,1,2,* Jun...
Peroxisome proliferator activated receptor-γ agonist pioglitazone improves vascular and metabolic dysfunction in systemic lupus erythematosus
Discussion CVD due to accelerated atherosclerosis is a significant contributor of morbidity and mortality in SLE and the effect of drugs currently used to treat SLE on improving cardiometabolic parameters and CV risk in SLE has not been systematically demonstrated.
Correspondence on ‘Clinical course of coronavirus disease 2019 (COVID-19) in a series of 17 patients with systemic lupus erythematosus under long-term treatment with hydroxychloroquine’
Correspondence on ‘Clinical course of coronavirus disease 2019 (COVID-19) in a series of 17 patients with systemic lupus erythematosus under long-term treatment with hydroxychloroquine’ Free http://orcid.org/0000-0001-8255-3554Sarthak Gupta, Shuichiro Nakabo, Jun Chu, Sarfaraz Hasni, http://orcid.org/0000-0003-2968-0815Mariana J Kaplan Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, USA...
Application of fluorescein combined with methylene blue in sentinel lymph node biopsy of breast cancer
Abstract Sentinel lymph node biopsy (SLNB) for axillary lymph node staging in early breast cancer has been widely recognized. The combination of radio-colloids and dye method is the best method recognized. The reagents and equipment required in the process of the combined method are complex and expensive, so there are certain restrictions in the use of primary medical institutions. As a new tracer, fluorescent tracer technology has attracted much attention.
Correspondence on ‘Clinical course of coronavirus disease 2019 (COVID-19) in a series of 17 patients with systemic lupus erythematosus under long-term treatment with hydroxychloroquine’
Correspondence on ‘Clinical course of coronavirus disease 2019 (COVID-19) in a series of 17 patients with systemic lupus erythematosus under long-term treatment with hydroxychloroquine’ Free http://orcid.org/0000-0001-8255-3554Sarthak Gupta, Shuichiro Nakabo, Jun Chu, Sarfaraz Hasni, http://orcid.org/0000-0003-2968-0815Mariana J Kaplan Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, USA...
Multivariate Metal-Organic Frameworks for Dialing-in the Binding and Programming the Release of Drug Molecules
We report the control of guest release profiles by dialing-in desirable interactions between guest molecules and pores in metal–organic frameworks (MOFs). The interactions can be derived by the rate constants that were quantitatively correlated with the type of functional group and its proportion in the porous structure; thus the release of guest molecules can be predicted and programmed.
Quantitative Multiscale Cell Imaging in Controlled 3D Microenvironments
A Microscope Designed for Multiscale Isotropic Imaging of Subcellular Biology in 3D Effects of 2D and 3D Microenvironments on Cell Morphology Multiscale Imaging Enables Simultaneous Observation of Subcellular Features and the Microenvironment Control over the Microenvironment Enables Observation of Spontaneous and Ubiquitous Pressure-Based Protrusions 3D Isotropic Resolution Enables Quantification of Protein Localization and Activity in Live Cells Blebs are characterized by uniform or regular...
Quantitative Multiscale Cell Imaging in Controlled 3D Microenvironments
Blebs are characterized by uniform or regular curvature. We measured the mean curvature at each triangular face as described in previous work (Figure S7x Download (1.12 MB ) Document S1. Figures S1–S7Figure S7G) (Elliott et al., 2015xMyosin II controls cellular branching morphogenesis and migration in three dimensions by minimizing cell-surface curvature. Elliott, H., Fischer, R.S., Myers, K.A., Desai, R.A., Gao, L., Chen, C.S., Adelstein, R.S., Waterman, C.M., and Danuser, G. Nat. Cell Biol.
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