Jun Lee on Muck Rack

Jun Lee

As seen in: Arthritis & Rheumatology, Color Research & Application, Nature, Wiley Online Library, American Journal of Health-System Pharmacy, PLOS, PLOS Medicine, PLOS ONE, ScienceDirect, BMJ Open and
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Articles

Scalable integrated framework for discovering high-performance MR-TADF emitters via combinatorial tree search

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By Yongkyu Lee, Uisung Lee, Jihoon Kang, Jangho Moon, Jonggeol Na, Jun Lee
| Nature Verified
Abstract Multi-resonance thermally activated delayed fluorescence (MR-TADF) materials are leading candidates for next-generation OLEDs, yet their discovery has remained slow due to intuition-driven design and limited scalable strategies for broad chemical spaces. Here, we report a scalable integrated framework that combines in silico exploration via combinatorial tree search with experimental validation, enabling end-to-end discovery of MR-TADF emitter cores.
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Association of cytochrome P450 2C19 genotypes with effectiveness of clopidogrel in ischemic stroke by smoking status

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By Hyungjong Park, Hye Sun Lee, Soyoung Jeon, Jinkwon Kim, Jong-Ho Park, Jae-Kwan Cha, Sung-Il Sohn, Sungwook Yu, Jun Lee, Kyung-Yul Lee, Tae-Jin Song, Hee-Kwon Park, Eung-Gyu Kim
| Nature Verified
Abstract Carriers of CYP2C19 loss-of-function (LOF) alleles have reduced clopidogrel bioactivation, higher on-treatment platelet reactivity, and more recurrent ischaemic events. Smoking may enhance clopidogrel responsiveness. We evaluated whether smoking modifies the impact of LOF alleles on clopidogrel effectiveness after acute ischaemic stroke.
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Therapeutic effect of intranasal nicotinamide adenine dinucleotide in the restoration of olfactory dysfunction

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By Jung Yeon Jang, Jun-Sang Bae, Eun Hee Kim, A Young Kim, Ji-Hun Mo, Jaewoo Park, Kyuho Kang, Jun Lee, Yong-Jae Kim, Dong-Joon Lee, Ji Heui Kim, Shin Hyuk Yoo, Reiza Ventura, Yeogyun Yun
| Nature Verified
Abstract Olfactory dysfunction is a debilitating condition with no established treatment. This study evaluated the efficacy of intranasal (i.n.) NAD administration in restoring olfactory function. Cultured human olfactory stem cells (hOSCs) were treated with NAD and assessed by immunofluorescence staining, PCR, and western blot analyses.
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