Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile
Articles by Jun Murai
Nonsense-mediated mRNA decay inhibition reshapes the cancer immunopeptidome
Keywords nonsense-mediated mRNA decay non-canonical neoantigens cryptic peptides cancer immunopeptidome SMG1 tumor immunogenicity cancer immunotherapy patient-derived fragments Introduction Effective anti-tumor immunity relies on the ability of T cells to detect cancer-associated peptides presented by the major histocompatibility complex (MHC) molecules and is shaped by both the quantity and quality of neoantigens.1,2 Among these, mutation-derived neoantigens (peptides derived from...
Nonsense-mediated mRNA decay inhibition reshapes the cancer immunopeptidome
|
Keywords nonsense-mediated mRNA decay non-canonical neoantigens cryptic peptides cancer immunopeptidome SMG1 tumor immunogenicity cancer immunotherapy patient-derived fragments Introduction Effective anti-tumor immunity relies on the ability of T cells to detect cancer-associated peptides presented by the major histocompatibility complex (MHC) molecules and is shaped by both the quantity and quality of neoantigens.1,2 Among these, mutation-derived neoantigens (peptides derived from...
By Roberto Vendramin, Hongchang Fu, Shanila Fernandez Patel, Yue Zhao, Danwen Qian, Lorena Ligammari, Osnat Bartok, Polina Greenberg, Ronen Levy, Andrea Castro, Krupa Thakkar, Jun Murai, Wei-Ting Lu, Christopher C.T. Sng, Chen Weller, Gordon Beattie, Amandeep Bhamra, Roc Farriol-Duran, Despoina Karagianni, Marcellus Augustine, Krijn K. Dijkstra, Christopher L. Pinder, Benjamin Simpson, Gordon Cheung, Felipe Galvez-Cancino, Petra Vlckova, Silvia Surinova, Manuel Rodriguez-Justo, Mansi Shah, Nicholas McGranahan, Jeremy G. Carlton, Eva Grönroos, James L. Reading, Yardena Samuels, Charles Swanton, Sergio A Quezada, Kevin Litchfield
|
Cell Press
Verified
Using a pan-cancer atlas to investigate tumour associated macrophages as regulators of immunotherapy response - Nature Communications
Abstract The paradigm for macrophage characterization has evolved from the simple M1/M2 dichotomy to a more complex model that encompasses the broad spectrum of macrophage phenotypic diversity, due to differences in ontogeny and/or local stimuli. We currently lack an in-depth pan-cancer single cell RNA-seq (scRNAseq) atlas of tumour-associated macrophages (TAMs) that fully captures this complexity.
Why cyber defense in Japan is so unreliable
For the past two years, people have struggled with the coronavirus pandemic, and part of that has entailed experiencing the benefits and challenges of cyberspace. In terms of challenges, we have experienced a great number of new incidents caused by the abuse and misuse of cyberspace.
Can Japan break away from its 'digital defeat'?
On Sept. 1, a new digital agency will be launched in Japan, and the Basic Law on the Formation of a Digitalized Society will come into effect, creating a digitally supported, resilient and horizontally connected structure that has the potential for creative development. With that, the Basic Law on the Formation of an Advanced Information and Telecommunications Network Society, which took effect on Jan.
Digital network building in the Pacific
Over the past few years, undersea cable projects, the key infrastructure for internet access across the globe, have become increasingly important for regional security and infrastructure with companies in the United States, Japan and Australia teaming up not only to ensure a stable telecommunications market, but also to approach geoeconomic concerns. On Jan. 13, the Palau government and the Belau Submarine Cable Corp.
Undersea internet cables offer more resilient connection
API Geoeconomic Briefing is a series provided by the Asia Pacific Initiative, an independent think tank based in Tokyo. The series will look into geopolitical and economic trends in the post-COVID-19 world, with a particular focus on technology and innovation, global supply chains, international rule-making and climate change.
Internet holds the key to the post-coronavirus era
API Geo-economic Briefing is a series provided by the Asia Pacific Initiative, an independent think tank based in Tokyo. The series will look into geopolitical and economic trends in the post-COVID-19 world, with a particular focus on four areas: technology and innovation; global supply chains; international rule-making and climate change.
Announcement regarding IPv4 Address Block 43/8
Prof Jun Murai presenting to university students. Image credit: Joi Ito As many people know, I have dedicated much of my career to the development of research networks and network technologies in Japan and Asia. This included the WIDE (Widely Integrated Distributed Environment) Project, founded in 1985 for computer networking R&D.
Show More
loading
Actions
Is this you?
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Get in touch with Jun
Contact Jun, search articles and posts on X, monitor coverage, and track replies from one place.
Learn more about Muck Rack