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Articles by Jun Sung
GDF15 Reprograms the Microenvironment to Drive Liver Metastasis of Uveal Melanoma Available to Purchase
The scRNA-seq and bulk RNA-seq data are available through GEO (#GSE317347: bulk RNA-seq and #GSE317349: scRNA-seq data). The ChIP-seq data are available through GEO (#GSE329586). All other raw data are available from the corresponding author upon request.
GDF15 Reprograms the Microenvironment to Drive Liver Metastasis of Uveal Melanoma Available
Uveal melanoma is an aggressive tumor type that frequently results in fatal liver metastasis. A better understanding of the interactions between uveal melanoma and host cells in the tumor microenvironment that promote liver metastasis could lead to the development of therapeutic strategies. In this study, we used single-cell RNA-sequencing analysis of uveal melanoma–hepatic stellate cell (HSC) cocultures to explore the mechanisms by which uveal melanoma cells metastasize to the liver.
GDF15 Reprograms the Microenvironment to Drive Liver Metastasis of Uveal Melanoma Available to Purchase
Uveal melanoma (UM) is an aggressive tumor type that frequently results in fatal liver metastasis. A better understanding of the interactions between UM and host cells in the tumor microenvironment that promote liver metastasis could lead to the development of therapeutic strategies. Here, we used single-cell RNA-sequencing (scRNA-seq) analysis of UM-hepatic stellate cell (HSC) co-cultures to explore the mechanisms by which UM cells metastasize to the liver.
Transoral thyroidectomy in a consecutive cancer-enriched cohort of 1–000 patients: a single-surgeon experience with endoscopic and robotic platforms
Abstract Introduction: Transoral vestibular thyroidectomy, performed using an endoscopic (transoral endoscopic thyroidectomy via the vestibular approach [TOETVA]) or robot-assisted (transoral robotic thyroidectomy [TORT]) approach, is a scar-concealing alternative to open thyroidectomy.
Ferroelectric switching of interfacial dipoles in α-RuCl₃/graphene heterostructure
Published January 6, 2026 | Version Published Journal Article Open Kim, Soyun1 Yun, Jo Hyun2, 3 Choe, Junsik1 Kim, Dohun1 Taniguchi, Takashi4 Watanabe, Kenji4 Falson, Joseph5 Kim, Jun Sung2, 3 Jin, Kyung-Hwan6 Cho, Gil Young3, 7 Kim, Youngwook1 1. Daegu Gyeongbuk Institute of Science and Technology 2. Pohang University of Science and Technology 3. Institute for Basic Science 4. National Institute for Materials Science 5. California Institute of Technology 6. Jeonbuk National University 7.
The CHANSE score: a novel clinical tool incorporating the heel drop test for the diagnosis of pediatric appendicitis
ORIGINAL RESEARCH article Volume 13 - 2025 | https://doi.org/10.3389/fped.2025.1724592 Introduction Acute appendicitis is one of the most common abdominal surgical emergencies among children presenting to the emergency department (1). Recent clinical guidelines emphasize that a combination of symptom characteristics, physical examination findings such as tenderness, and laboratory evidence of inflammation can enable accurate diagnosis in the majority of suspected appendicitis cases (2).
Methionyl-tRNA synthetase 1 expression, the possibility as a diagnostic and prognostic factor in papillary thyroid cancer - BMC Cancer
Abstract Methionyl-tRNA synthetase 1 (MARS1) is a critical enzyme in translation initiation, responsible for catalyzing the transfer of Met to the initiator tRNA. In this study, we aimed to examine whether MARS1 expression is different between normal follicular cells and papillary thyroid carcinoma (PTC) cells in thyroid tissue and whether it can supplement the limitations of general cell staining methods currently performed for diagnosis of PTC.
Anti-thyroglobulin antibody levels post-thyroidectomy and papillary thyroid carcinoma recurrence - BMC Cancer
This retrospective study enrolled 15,620 patients with thyroid cancer who underwent bilateral total thyroidectomies for thyroid cancer at Gangnam Severance Hospital Thyroid Cancer Center between March 2004 and December 2022.
Anti-thyroglobulin antibody levels post-thyroidectomy and papillary thyroid carcinoma recurrence - BMC Cancer
Abstract The global incidence of thyroid cancer, particularly papillary thyroid carcinoma (PTC), is rising due to more frequent incidental findings. Despite a high 10-year survival rate of 93%, up to 28% of PTC patients experience locoregional recurrence. Postoperative monitoring typically relies on serum thyroglobulin (Tg), but the presence of anti-thyroglobulin antibodies (TgAb) interferes with Tg measurement, necessitating reliable detection methods.
Correction: Park et al. Immunization effects of a novel α-synuclein-based peptide epitope vaccine in Parkinson’s Disease-associated pathology. Vaccines 2023, 11, 1820
Park, Jun Sung, Ahmad, Riaz, Choe, Kyonghwan, Kang, Min Hwa, Park, Tae Ju and Kim, Myeong Ok (2025) Correction: Park et al. Immunization effects of a novel α-synuclein-based peptide epitope vaccine in Parkinson’s Disease-associated pathology. Vaccines 2023, 11, 1820. Vaccines, 13(5), 512. (doi: 10.3390/vaccines13050512) (PMID:40432159) (PMCID:PMC12116145) Text 357193.pdf - Published Version Available under License Creative Commons Attribution. 5MB Abstract No abstract available.
The association between initial post-resuscitation diastolic blood pressure and survival after pediatric cardiac arrest: a retrospective study - BMC Pediatrics
References McNally B, Robb R, Mehta M, Vellano K, Valderrama A, Yoon P, et al. Centers for disease control and prevention. Out-of-hospital cardiac arrest surveillance—cardiac arrest Registry to enhance survival (CARES), United States, October 1, 2005–December 31, 2010. MMWR Surveill Summ. 2011;60(8):1–19. PubMed Google Scholar Morgan RW, Kirschen MP, Kilbaugh TJ, Sutton RM, Topjian AA. Pediatric in-hospital cardiac arrest and cardiopulmonary resuscitation in the United States: a review. JAMA Pediatr.
Immunization effects of a novel α-synuclein-based peptide epitope vaccine in Parkinson’s Disease-associated pathology
Park, J. S., Ahmad, R., Choe, K., Kang, M. H., Park, T. J. and Kim, M. O. (2023) Immunization effects of a novel α-synuclein-based peptide epitope vaccine in Parkinson’s Disease-associated pathology. Vaccines, 11(12), 1820. (doi: 10.3390/vaccines11121820) (PMID:38140224) (PMCID:PMC10748214) Text 314942.pdf - Published Version Available under License Creative Commons Attribution.
Exploring shared neural substrates underlying cognition and gait variability in adults without dementia - Alzheimer's Research & Therapy
This study is embedded in the Korean Longitudinal Study on Cognitive Aging and Dementia (KLOSCAD), a population-based prospective multicenter cohort study of Koreans aged 60 years and older. The KLOSCAD was launched in 2009 and was followed up biennially until 2020 [20].
The rice NUCLEAR FACTOR-YA5 and MICRORNA169a module promotes nitrogen utilization during nitrogen deficiency
Nitrogen (N) is essential for plant growth and development. Therefore, understanding its utilization is essential for improving crop productivity. However, much remains to be learned about plant N sensing and signaling. Here, rice (Oryza sativa) NUCLEAR FACTOR-YA5 (OsNF-YA5) expression was tightly regulated by N status and induced under N-deficient conditions.
Neuroprotective effects of osmotin in Parkinson’s disease-associated pathology via the AdipoR1/MAPK/AMPK/mTOR signaling pathways - Journal of Biomedical Science
Human neuroblastoma SH-SY5Y cells were purchased from Korea Cell Line Bank (KCLB, South Korea) and cultured in Dulbecco’s modified Eagle’s medium (DMEM; Gibco, NY, USA) containing a 1% antibiotic–antimycotic solution and 10% fetal bovine serum at 37 °C with 5% CO2. The mHippoE-14 embryonic mouse hippocampal cell line (Cedarlane, Canada) was derived at embryonic Day 14 and cultured in DMEM without sodium pyruvate.
Lateral neck dissection for the treatment of synchronous and metachronous lateral neck metastasis of N1b papillary thyroid cancer
1 Introduction A significant increase in the incidence of papillary thyroid cancer (PTC), mainly owing to the expansion of diagnostic imaging, has been reported worldwide (1–3). Although mortality associated with PTC remains low, it has been suggested that the ability to detect small, relatively indolent tumors by radiographic examination may be improved, which may lead to overdiagnosis (1, 4). However, data from the past decade have shown conflicting results.
Spatial genomics maps the structure, nature and evolution of cancer clones
Nature, Feb 2023 This is a preview of a remote PDF: https://www.nature.com/articles/s41586-022-05425-2.pdf Lomakin, Artem, Svedlund, Jessica, Strell, Carina, Gataric, Milana, Shmatko, Artem, Rukhovich, Gleb, Park, Jun Sung, Ju, Young Seok, Dentro, Stefan, Kleshchevnikov, Vitalii, Vaskivskyi, Vasyl, Li, Tong, Bayraktar, Omer Ali, Pinder, Sarah, Richardson, Andrea L., Santagata, Sandro, Campbell, Peter J., Russnes, Hege, Gerstung, Moritz, Nilsson, Mats, Yates, Lucy R..
Establishing co-culture blood-brain barrier models for different neurodegeneration conditions to understand its effect on BBB integrity
Park, J. S., Choe, K., Khan, A., Jo, M. H., Park, H. Y., Kang, M. H., Park, T. J. and Kim, M. O. (2023) Establishing co-culture blood–brain barrier models for different neurodegeneration conditions to understand its effect on BBB integrity. International Journal of Molecular Sciences, 24(6), 5283. (doi: 10.3390/ijms24065283) Text 294609.pdf - Published Version Available under License Creative Commons Attribution.
Cell2location maps fine-grained cell types in spatial transcriptomics - Nature Biotechnology
Abstract Spatial transcriptomic technologies promise to resolve cellular wiring diagrams of tissues in health and disease, but comprehensive mapping of cell types in situ remains a challenge. Here we present сell2location, a Bayesian model that can resolve fine-grained cell types in spatial transcriptomic data and create comprehensive cellular maps of diverse tissues.
Deep-ultraviolet electroluminescence and photocurrent generation in graphene/hBN/graphene heterostructures - Nature Communications
Abstract Hexagonal boron nitride (hBN) is a van der Waals semiconductor with a wide bandgap of ~ 5.96 eV. Despite the indirect bandgap characteristics of hBN, charge carriers excited by high energy electrons or photons efficiently emit luminescence at deep-ultraviolet (DUV) frequencies via strong electron-phonon interaction, suggesting potential DUV light emitting device applications. However, electroluminescence from hBN has not been demonstrated at DUV frequencies so far.
Support GSOC to Protect NYU
The Graduate Employees’ Organization at the University of Michigan organized a strike on Sept. 8 in response to the university’s plans to reopen its campus and the lack of transparency regarding COVID-19 policies from the university. For a week, a large portion of university labor stopped. Dining workers initiated a work slowdown and unionized truck drivers and construction workers stopped working on campus as well.
The Consequences of NYU’s Guise of Transparency
Friday, May 1 was decision day, when many high school seniors chose where they were going to go to college for the next four years. This year’s day was unprecedented with campuses unavailable for in-person visits that were supposed to help with making this decision. Even in the midst of everything, some upcoming members of the class of 2024 posted on social media with #NYU2024 in excitement for the future.
The Graduate School of Arts and Sciences Must Do More For Its Students
Last week, the COVID-19 Coalition and NYU’s Graduate Student Organizing Committee hosted a Virtual Week of Action, which sought to raise awareness of the demands brought up by the coalition. One of these actions was an open letter from GSOC to Provost Katherine Fleming that voiced concerns about the challenges faced by graduate students after the closure of campus while also arguing for the universal extension of both time-to-degree deadlines and funding packages.
Prioritizing Transparency in Federal Relief Spending
The Department of Education recently released the amount of funding certain universities will receive through the CARES Act — the third installment of the coronavirus stimulus plan from Congress. NYU will receive the second highest amount among non-profit, private institutions at $25,626,944. However, as reported by NYU Local, this money comes with conditions. 50% must be used to provide students with emergency costs like food, technology and healthcare.
New Yorkers Don’t Deserve Petty Politics
On Saturday, April 11, New York City Mayor Bill de Blasio closed public schools for the remainder of the academic year due to concerns over the spread of the coronavirus as well as the trauma children are experiencing during the pandemic. Soon after, New York State Governor Andrew Cuomo overturned that decision, claiming that the state — not the city — has authority over the closure of public schools during this crisis.
Holding Leaders More Accountable in Crisis, Not Less
During this time of crisis, New York State Governor Andrew Cuomo has become a figure of admiration for many Americans looking for a dependable political authority to feel protected. After Cuomo’s daily press conferences, the hashtag #PresidentCuomo can be seen on Twitter, and numerous articles have been published praising Cuomo for his responses against COVID-19.
The Principled Necessity of Tuition Reimbursement
On Monday, March 16, NYU President Andrew Hamilton announced the university would be transitioning to online classes due to the spread of the novel coronavirus.
NYU’s Evictions Show Its Disregard for Students’ Needs
Last Monday, NYU President Andrew Hamilton sent out a letter to the student body about the closure of residence halls and the transition to online classes for the rest of the semester. Though residences would be officially closed on Sunday, March 22, it was recommended that students move out within 48 hours. This happened days after a number of universities — including Stanford, Harvard and Columbia — had already decided to transition to online classes.
Expanding Accessibility to Paid Sick Leave
Over the past week, the number of coronavirus cases in New York State has risen, leading Governor Andrew Cuomo to declare a state of emergency. As more cases are diagnosed, the Centers for Disease Control and Prevention has recommended that employers encourage sick employees to stay home. The CDC has also advised individuals who are showing signs of the disease to quarantine themselves for 14 days. For New York’s workers, the situation is both financially and physically detrimental.
Confronting the Contradiction of NYU Abu Dhabi
The year 2020 marks the 10th anniversary of NYU Abu Dhabi’s campus. To celebrate, the university is planning various events that give members of the community the opportunity to share stories about their experiences. But it is doubtful that these events will include the darker aspects of the campus. In its short history, NYUAD has been mired in controversy.
Incompetence and Disaster in the Democratic Party
On Feb. 6, President Trump was acquitted of his impeachment charges by the United States Senate. This was after the House of Representatives impeached him over a whistleblower’s complaint, claiming he asked Ukrainian President Volodymyr Zelensky to investigate former Vice President Biden, a candidate in the Democratic primary, and his son, Hunter Biden. The two articles brought against him were accusations of abuse of power and obstruction of Congress.
Interpreting Silence: What NYU’s Low Title IX Complaints Mean
On Jan. 27, the New York State Education Department released its data report on Title IX complaints from college campuses across the state. It is a result of the “Enough is Enough” law passed in the state legislature, which was meant to create a set of procedures and guidelines that support victims of sexual assault, domestic violence, dating violence and stalking. NYU was included in the report, but the results show the problematic nature of the university’s safety nets.
The Significant Climate Impact of the USMCA
On Jan. 29, President Trump signed into law the United States-Mexico-Canada-Agreement, a free trade agreement between the United States, Mexico and Canada that builds upon the North American Free Trade Agreement, which went into effect in 1994. The deal is not yet approved by all three countries. It has to go through Canada’s parliament, where it will likely face little resistance.
The Significant Climate Impact of the USMCA
With the likely implementation of the USMCA in North America, it is important to understand its disastrous effects on the environment. By Jun Sung, Opinion Editor January 31, 2020 On Jan. 29, President Trump signed into law the United States-Mexico-Canada-Agreement, a free trade agreement between the United States, Mexico and Canada that builds upon the North American Free Trade Agreement, which went into effect in 1994. The deal is not yet approved by all three countries.
The University’s Place in the Climate Crisis
Wildfires have raged in Australia since Jul. 2019, killing 28 people and millions of animals. They have burned through the continent with about 12.35 million acres of land damaged, affecting every state. Experts say hotter and drier conditions have led to a more amplified and destructive bushfire season. These fires must be analyzed in direct connection with the climate crisis; failure to do so means failure to recognize the most obvious truths on the climate crisis.
Athletes Are Human Too
Last Wednesday, the Brooklyn Nets faced the Boston Celtics in Boston, marking Kyrie Irving’s first return to Boston since signing with the Nets. Though Irving was out for the game with an injury, Celtics fans, who blamed Irving as the main culprit of the much-publicized toxicity surrounding the team in the past season, hurled heavy vitriol as resounding “Kyrie sucks” chants echoed throughout TD Garden.
Kanye West and the Commodification of Christianity
Kanye West released “Jesus Is King” on Oct. 25, an album showcasing his reconnection with Christianity. Though it may seem like a newfound dedication to Christ, the reality is that the project is a commodification of Christianity. In addition, it is a part of a larger trend in the United States of normalizing the teachings of the prosperity gospel, and the effects of the religious fringe on both the culture and politics of the country.
The Necessity of Protesting on Privileged Ground
The annual Harvard-Yale football game was disrupted on Saturday by student activists from Divest Harvard, Yale Endowment Justice Coalition and Fossil Free Yale who demanded that the two universities divest from the fossil fuel industry and Puerto Rican debt. After almost an hour of delay, some protesters were taken off the field while those who remained were arrested.
De Blasio’s Abysmal Attempt at Homeless Outreach
Mayor Bill de Blasio launched Outreach NYC last week, which aims to address the city’s homelessness issue. The program encourages city workers to contact a command center when they see a homeless person on the street, which then dispatches teams that try to persuade homeless individuals to get off the streets and into city facilities. There are serious issues with this program, as it simply serves aesthetics and fails to pinpoint the root causes of homelessness in the city.
Disney+ Is a Cash Grab
This week saw the launch of Disney+, a new streaming service exclusively for Disney content. The practice of keeping content exclusive is damaging and reminds us of Disney’s desire as an industry giant to take advantage of consumers and monopolize the market. By creating Disney+, Disney is taking advantage of consumers’ childhood nostalgia.
Bloomberg and the Politics of Class Struggle
On Nov. 8, former New York City Mayor Michael Bloomberg filed to run in the Alabama Democratic Primary. His advisors say that he is running because he believes the candidates in the primary will not be able to beat Trump. However, his candidacy is just a sign of solidarity with the elite class and a direct reaction to the rise of the left in the United States. Bill Gates’ recent comments on Sen. Elizabeth Warren’s (D-Massachusetts) wealth tax plan is emblematic of this elitist unity.
Stop U.S. Base Relocation in Okinawa
Last December, the Japanese government started landfill work in Okinawa as part of its efforts to relocate the U.S. military base from Futenma to Henoko. This plan is in response to local outrage over problems like aircraft accidents and serious crimes by U.S. military personnel. Residents have been protesting against this project, arguing that the construction process will have severe environmental consequences and that the U.S. military should leave the island altogether.
Short-Term Walking Outcomes in Diabetic and Non-Diabetic Unilateral Transtibial Amputees
Short-Term Walking Outcomes in Diabetic and Non-Diabetic Unilateral Transtibial Amputees Dong Gyu Kwak,1 Jeong-Yong Hur,2 Jun Sung Moon,3 and Min Cheol Chang1 1Department of Physical Medicine and Rehabilitation, Yeungnam University College of Medicine, Daegu, Korea. 2Shinsegae Prosthesis & Orthosis Center, Korea. 3Division of Endocrinology and Metabolism, Department of Internal Medicine, Yeungnam University College of Medicine, Daegu, Korea. Corresponding author: Jun Sung Moon.
Vote Yes on Ballot Question 1
New York City residents will be able to vote on Nov. 5 whether or not to implement a ranked-choice voting system for local primaries and certain special elections. Under this system, voters rank their preferred candidates at the ballot. If no candidate gains a majority vote, the worst-performing candidate is eliminated and the votes are reallocated according to a voter’s ranking. This process would continue until a candidate gains the majority.
New York’s Homeless Deserve Safer Shelters
Earlier this month, four homeless men were killed in Chinatown, and one was critically injured. The situation reveals the dangers of living on the street and is emblematic of New York City’s housing crisis as well. However, it also poses the question of why these individuals were not in homeless shelters. A friend of Chuen Kwok, one of the men killed in the attacks, said Kwok avoided homeless shelters because he found that the streets were safer than the facilities.
NYC Law Enforcement Needs to be Held Accountable
Oriel Ceballos, a local artist who frequently displays his work in Washington Square Park, was violently arrested last week by law enforcement. A video taken by a bystander in the park shows multiple officers tackling Ceballos to the ground and pepper-spraying him. Considering that Ceballos was arrested because he put his art on the ground rather than on a table, the reaction from law enforcement was exaggerated and unnecessary.
The Myth of Unpaid Internships
The 2020 Democratic primary has presented a plethora of candidates, each one pledging to improve the political and social dysfunction in the United States. One of these dysfunctions that has been addressed is the outrageous cost of attending college. A proposed solution is the concept of free tuition at four-year public universities. This would provide, particularly to those of lower socioeconomic classes, the opportunity to fulfill their goals.
Trump Is Trying to Dilute the Meaning of Impeachment
Impeachment is finally upon us. From scandal to scandal, the country has been waiting to see when House Speaker Nancy Pelosi would pull the trigger, and the moment has finally arrived — an inquiry has been opened in the aftermath of the Ukraine whistleblower debacle. But again, President Donald Trump is arming himself with his greatest political weapon: his ability to trivialize chaos. Impeachment is a political rarity.
NYU Isn’t Doing Enough for Religious Students
From before I learned to speak to the time I graduated high school, I attended the same Jewish school. Class was not only canceled for religious holidays — it revolved around them. In advance of Rosh Hashanah and Yom Kippur, arguably the holiest days in the Jewish calendar, we devoted class time to self-reflection and education on the unique practice of each holiday.
Paywalls Contribute to the Gatkeeping of Information
It’s the eternal struggle of trying to read The New York Times online. One article, three articles, five articles, then you hit a paywall, prompting you to buy a subscription to read further. As of 2018, this is the case for 78% of U.S. media, including The Times, The Wall Street Journal and The Washington Post. For organizations whose purpose is to inform the public, this elitist gatekeeping of information can have consequences.
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