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Articles by Junjun He
SlideChat is a multimodal generative artificial intelligence assistant for whole-slide computational pathology across cancer types
Abstract Multimodal artificial intelligence, albeit showing great potential in computational pathology, remains limited to isolated patch-level interpretation and often fails to analyze gigapixel-scale whole-slide images (WSIs) essential for clinical utility. Here we present SlideChat, a multimodal generative artificial intelligence assistant for whole-slide computational pathology across cancer types.
HealthFlow: automating electronic health record analysis via a strategically self-evolving multi-agent framework
Abstract Electronic health records (EHRs) are a rich source of real-world clinical data, but turning them into valid analyses remains slow, brittle, and expert-intensive. Although recent AI agents can answer medical questions and use tools, automating full EHR workflows remains difficult because small planning or execution errors can invalidate otherwise plausible analyses.
A triaxial benchmark for assessing responses from large language models in traditional Chinese medicine
Abstract Large language models (LLMs) show promise in specialized domains, but their capabilities in Traditional Chinese Medicine(TCM)—a field with complex theoretical foundations and clinical practices—remain inadequately assessed. This study aims to develop and apply a comprehensive, multidimensional benchmark to systematically evaluate LLM proficiency in this culturally-grounded medical discipline.
ZmMYB127 controls maize endosperm filling via dual-transcriptional regulation to improve grain yield and quality
Abstract As the main nutrient reservoir in cereal grains, the endosperm largely determines grain yield, performance and nutrition. However, knowledge of genes that coordinate endosperm filling and nutrient deposition, which could offer potential for genetic improvement of grain traits, remain limited. Here we identified ZmMYB127, a filling-endosperm-specific MYB transcription factor.
Optimizing Sintering Temperature for Enhanced Piezoelectric Performance in PMT-PNT-PZT Ceramics
Submitted: 27 January 2026 You are already at the latest version 0.006Pb(Mn1/3Ta2/3)O3-0.114Pb(Ni1/3Ta2/3)O3-0.43PbZrO3-0.45PbTiO3 lead-based ceramics (PMT-PNT-PZT) were synthesized via the solid-state reaction at different sintering temperatures to study their effects on phase structure, microstructure, and electrical properties. The maximum mechanical quality factor (Qm) and relative permittivity (εr) were achieved at the sintering temperature of 1200 °C.
Plasma‐Based Genomic Features Influencing Outcomes of T790M‐Positive Non-Small Cell Lung Cancer Receiving Osimertinib
1 Introduction Epidermal growth factor receptor (EGFR) mutation is recognized as one of the most important targets in patients with advanced non–small cell lung cancer (NSCLC), and EGFR tyrosine kinase inhibitor (EGFR-TKI) administration is the standard treatment for NSCLC patients carrying EGFR sensitive mutations. Osimertinib, a third-generation EGFR-TKI, is now used as a first-line strategy for EGFR-positive NSCLC patients [1].
Parabacteroides distasonis promotes CXCL9 secretion of tumor-associated macrophages and enhances CD8+T cell activity to trigger anti-tumor immunity against anti-PD-1 treatment in non-small cell lung cancer mice | BMC Biotechnology | Full Text
To explore the effect of P. distasonis on tumor immunity, C57BL/6 male immunocompetent mice (8 weeks of age) were used in this study. Subcutaneously, 2 × 106 Lewis lung cancer cells (LLC, AW-CCM076, derived from the C57BL/6 mouse NSCLC cell line) were inoculated into left axilla of mice to establish a mouse model of Lewis lung cancer [25]. Experiment 1: The mice were randomly divided into four groups: PBS, P. distasonis, αPD-1, and αPD-1 + P. distasonis, five mice in each group. Mice in P.
Occurrence and Molecular Characterization of Cryptosporidium spp. in Beef Cattle in Yunnan Province, China
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Prognostic value of pretreatment systemic immune-inflammation index in patients with endometrial cancer: a meta-analysis
Papers of special note have been highlighted as: • of interest; • • of considerable interest • None Annual report to the nation on the status of cancer, part I: National cancer statistics . 126(10), 2225–2249 ( ). • None Carcinoma of the corpus uteri. FIGO 26th Annual Report on the Results of Treatment in Gynecological Cancer . 95(Suppl. 1), S105–143 ( ). • None Pre-treatment neutrophil to lymphocyte ratio as a biomarker of frailty and predictor of survival among older adults with multiple myeloma .
Prognostic Role of Geriatric Nutritional Risk Index in Patients with Pancreatic Cancer: A Meta-Analysis
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FCN+: Global Receptive Convolution Makes FCN Great Again
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