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Dephosphorylation of FLA8/KIF3B Is Regulated by Okadaic-Acid-Sensitive Phosphatases, but Not PP2A Both CrPP1 and CrPP6 Participate in FLA8 Dephosphorylation Double Depletion of CrPP1 and CrPP6 Leads to Elevation of pFLA8 in Steady-State Cells and Short Flagella As PP1 is a target of okadaic acid and PP6 is a potential target of okadaic acid that regulates aurora A (AURKA), a kinase involved in ciliary functions [20xProtein phosphatase 6 regulates mitotic spindle formation by controlling the...
Keywords: Bug22, Chlamydomonas, Cilia motility, Flagella, Cilia, Planar beating Motile cilia and eukaryotic flagella typically contain a ‘9+2’ arrangement of axonemal microtubules attached with accessory structures, such as dynein arms and radial spokes, that are necessary for motility (Porter and Sale, 2000). In spite of this common structure, the beat patterns of cilia and flagella vary from a ciliary-type to a flagellar-type waveform.
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