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Junying Ma

As seen in: Nature, Wiley Online Library, ACS Publications
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Articles

Mutations in ClpC1 or ClpX subunit of caseinolytic protease confer resistance to ilamycins in mycobacteria - Communications Biology

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By Junying Ma, Xiaoli Xiong, Jianhua Ju
| Nature Verified
Abstract The mycobacterial caseinolytic protease (Clp) system has been recognized as a promising therapeutic target. In this study, we identify two novel ilamycin analogs, ilamycin E (ILE) and ilamycin F (ILF), both targeting the ClpC1 component of the ClpC1P1P2 proteasome. ILE potently disrupts ClpC1P1P2-mediated proteolysis, leading to delayed bactericidal activity, while ILF also binds ClpC1, albeit with lower affinity.
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Base‐Promoted [4+2] Annulation for the Synthesis of Tri‐Aryl Substituted α‐Pyrones

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By Mengdan Wang, Jianyue Li, Junying Ma, Junling Wang
| Wiley Online Library Verified
Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
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Selective Synthesis of Cyclopeptides with a 2-Oxindole or 3a-Hydroxy-hexahydropyrrolo-[2,3-b]indole Structure by Cytochrome P450 Enzymes

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By Junying Ma, Lu Guo, Chao Xu, Zijian Zhong
| ACS Publications
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