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Zijian Zhong

As seen in: Nature, ACS Publications
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Articles

Cytosolic CTH senses bacterial lipoproteins and drives noncanonical inflammasome activation

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By Qiannv Liu, Chunlei Wang, Mengqian Li, Zijian Zhong, Xiangyun Cheng, Zhixia Li, Dong Jiang, Xiuli Sun, Shuo Wang, Pengyan Xia, Chun Kong, Xiangyang Geng, Chongyao Zhong
| Nature Verified
Abstract Pathogen-associated molecules can have both membrane-associated and intracellular receptors. Bacterial lipoproteins are recognized by Toll-like receptor 2, but it is unclear whether they can also be sensed by cytoplasmic receptors. Here we found that bacterial lipoproteins could be recognized in the cytoplasm of macrophages by cystathionine γ-lyase (CTH) and hydrolyzed into lipid chains containing sulfhydryl groups.
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Selective Synthesis of Cyclopeptides with a 2-Oxindole or 3a-Hydroxy-hexahydropyrrolo-[2,3-b]indole Structure by Cytochrome P450 Enzymes

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By Junying Ma, Lu Guo, Chao Xu, Zijian Zhong
| ACS Publications
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Selective Synthesis of Cyclopeptides with a 2-Oxindole or 3a-Hydroxy-hexahydropyrrolo-[2,3-b]indole Structure by Cytochrome P450 Enzymes

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By Junying Ma, Lu Guo, Chao Xu, Zijian Zhong
| dx.doi.org
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