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Junying Zheng

As seen in: Nature, Wiley Online Library, Cell Press
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Articles

Dorsal horn DCC amplification loop induced by endplate osteoclasts generates chronic nociplastic low back pain in male mice

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By Dayu Pan, Mengxi Shen, Jinjian Zheng, Damien Laudier, Chao Kong, Zhaozhu Qiu, James C. Iatridis, Mei Qi Wan, Junying Zheng, Bradley Taylor, Xu Cao, Elizabeth Abatan, Philip Nasser
| Nature Verified
Abstract Spine degeneration is associated with low back pain (LBP), a major cause of disability and functional decline. However, effective therapies for non-specific LBP remain limited because its underlying mechanisms are poorly understood. Here, we show that spine degeneration induces netrin-1 secretion in porous endplates to activate DCC signaling in dorsal root ganglion (DRG) neurons in both LBP and naturally aged male mice.
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Identification of a reactive astrocyte subpopulation during HIV-associated pain pathogenesis in mouse models - Nature Communications

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By Junying Zheng, Sakib Hossain, Michael Spurgat, Adriana Dibua
| Nature Verified
Abstract Pain is a common complication in individuals with HIV, yet the underlying pathogenic mechanisms remain poorly understood. Reactive astrocytes are selectively activated in the spinal dorsal horn of HIV patients experiencing pathological pain, implicating their potential role in pain pathogenesis. However, the specific pathogenic subtype of these reactive astrocytes has not been defined.
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Selective sensing of hexavalent chromium in food grains using an electrodeposited bimetallic Au‐Pd nanoparticles modified electrode

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By Junying Zheng, Yi Zhang, Lei Huang, Xiaoping Wu
| Wiley Online Library Verified
Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Filename Description elan202400028-s1-SI_1.docx624.2 KB Supplementary elan202400028-s2-SI_2.docx524.9 KB Supplementary
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