Justine Barletta
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Higher SUVmax on FDG-PET is associated with shorter survival in adrenocortical carcinoma
Adrenocortical carcinoma (ACC) is an aggressive, rare malignancy. 2-deoxy-2-[18F]-fluoro- -glucose positron emission tomography (FDG-PET) assesses tumor metabolism and glucose utilization. We hypothesized that higher maximum standard uptake value (SUV ) is associated with decreased survival. We performed a retrospective analysis of patients with ACC. Included patients (n = 26) had an FDG-PET scan available with a documentable SUV .
Management of thyroid nodules
1. Diagnosis of thyroid nodules. Lancet Diabetes Endocrinol. 2022; 10: 533-539 2. Baloch ZW Asa SL Barletta JA et al. Overview of the 2022 WHO classification of thyroid neoplasms. Endocr Pathol. 2022; 33: 27-63 3. Namba H Matsuo K Fagin JA Clonal composition of benign and malignant human thyroid tumors. J Clin Invest. 1990; 86: 120-125 4. Marcadis AR Valderrabano P Ho AS et al.
Hürthle cell neoplasms
Abstract Hürthle cells (HC) are characterized by abundant granular eosinophilic cytoplasm containing accumulated dysfunctional mitochondria and large nuclei with prominent nucleoli. Based on the distinct clinicopathologic and molecular characteristics of Hürthle cell neoplasms (HCN), the 2017 Endocrine World Health Organization (WHO) moved to categorizing HCN as a separate group of tumors.
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