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Juvan Vairamuthu on Muck Rack

Juvan Vairamuthu

As seen in: Cell Press
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Articles

Caspase-4 binds to LPS membranes with positive curvature for non-canonical inflammasome activation

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By Jakub Began, Alexandra Boegli, Leonie Anton, Denys Biriukov, Jose Santos, Petr Broz, Juvan Vairamuthu
| Cell Press Verified
Keywords innate immunity inflammasomes caspase-4 lipopolysaccharide sensing LPS GBP1 membrane curvature Introduction Lipopolysaccharide (LPS) is the major structural component of the outer membrane of Gram-negative bacteria and a strong activator of immune cells, including monocytes, macrophages, and dendritic cells.
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