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Juzhen Yin on Muck Rack

Juzhen Yin

As seen in: Journal of Infection
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Articles

Repeated Omicron infection dampens immune imprinting from previous vaccination and induces broad neutralizing antibodies against Omicron sub-variants

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By Xiaohua Gong, Ling Peng, Fuxiang Wang, Jiexiang Liu, Yimin Tang, Yun Peng, Shiyu Niu, Juzhen Yin, Liping Guo, Hongzhou Lu, Yingxia Liu
| Journal of Infection Verified
Abstract Similar with influenza virus, antigenic drift is highly relevant to SARS-CoV-2 evolution, and immune imprinting has been found to limit the performance of updated vaccines based on the emerging variants of SARS-CoV-2. We aimed to investigate whether repeated exposure to Omicron variant could reduce the immune imprinting from previous vaccination.
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