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Yingxia Liu on Muck Rack

Yingxia Liu

As seen in: Nature, JAMA: Journal of the American Medical Association, Future Medicine, Journal of Infection
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Articles

Rubisco supplies pyruvate for the 2-C-methyl-d-erythritol-4-phosphate pathway - Nature Plants

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By Sonia E. Evans, Yuan Xu, Matthew E. Bergman, Scott Ford, Yingxia Liu, Thomas D. Sharkey
| Nature Verified
Abstract RIBULOSE-1,5-BISPHOSPHATE CARBOXYLASE/OXYGENASE (Rubisco) produces pyruvate in the chloroplast through β-elimination of the aci-carbanion intermediate1. Here we show that this side reaction supplies pyruvate for isoprenoid, fatty acid and branched-chain amino acid biosynthesis in photosynthetically active tissue. 13C labelling studies of intact Arabidopsis plants demonstrate that the total carbon commitment to pyruvate is too large for phosphoenolpyruvate to serve as a precursor.
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Evolutionary trajectory and characteristics of Mpox virus in 2023 based on a large-scale genomic surveillance in Shenzhen, China - Nature Communications

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By Shengjie Zhang, Fuxiang Wang, Jing Yuan, Yingxia Liu
| Nature Verified
Abstract The global epidemic of Mpox virus (MPXV) continues, and a local outbreak has occurred in Shenzhen city since June 2023. Herein, the evolutionary trajectory and characteristics of MPXV in 2023 were analyzed using 92 MPXV sequences from the Shenzhen outbreak and the available genomes from GISAID and GenBank databases. Phylogenetic tracing of the 92 MPXVs suggests that MPXVs in Shenzhen may have multiple sources of importation, and two main transmission chains have been established.
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Repeated Omicron infection dampens immune imprinting from previous vaccination and induces broad neutralizing antibodies against Omicron sub-variants

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By Xiaohua Gong, Ling Peng, Fuxiang Wang, Jiexiang Liu, Yimin Tang, Yun Peng, Shiyu Niu, Juzhen Yin, Liping Guo, Hongzhou Lu, Yingxia Liu
| Journal of Infection Verified
Abstract Similar with influenza virus, antigenic drift is highly relevant to SARS-CoV-2 evolution, and immune imprinting has been found to limit the performance of updated vaccines based on the emerging variants of SARS-CoV-2. We aimed to investigate whether repeated exposure to Omicron variant could reduce the immune imprinting from previous vaccination.
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