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Kai-Yin Lee on Muck Rack

Kai-Yin Lee

As seen in: Science Magazine, EJSO - European Journal of Surgical Oncology
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Articles

Healthy donor T cell receptors expand functional neoantigen recognition beyond patient vaccination

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By Hong Kai Teo, Soham Basu, Alexandre Bouyssou, Shuting Han, Thamizhanban Manoharan, Yi Ren, Zhewang Lin, Jiaqi Li, Si-Lin Koo, Choon Kong Yap, Kai-Yin Lee, Who-Whong Wang, Malini Rethnam, Bei-En Siew, Gwyneth Shook-Ting Soon, Wai-Kit Cheong, Ian Jse-W
| Science Magazine Verified
Abstract A major challenge in advancing neoantigen-targeted therapies lies in the limited capacity of predicted neoantigens to robustly activate CD8+ T cells, emphasizing the critical need for comprehensive functional validation before patient vaccination. Here, we provide a direct comparison of neoantigen-specific T cell responses between vaccinated patients with cancer and HLA-matched healthy donors.
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The impact of colorectal cancer on quality of life of younger adults: A qualitative longitudinal approach

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By Jerrald Lau, Alyssa Isabelle Ng, Kai-Yin Lee, Ian Tan
| EJSO - European Journal of Surgical Oncology Verified
Keywords Colorectal cancer Quality of life Qualitative Coping Experiences Get full text access Log in, subscribe or purchase for full access. References 1. Organization WH. Colorectal Cancer Fact Sheet. World Health Organization. 2023. https://www.who.int/news-room/fact-sheets/detail/colorectal-cancer. 2. Siegel, R.L. ∙ Wagle, N.S. ∙ Cercek, A. ... Colorectal cancer statistics, 2023 CA Cancer J Clin. 2023; 73:233-254 3. Sung, H. ∙ Siegel, R.L. ∙ Laversanne, M. ...
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