Kai Yu Ng

Abstract Increasing evidence indicates that activation of oncogenic pathways contributes to an unfavourable tumour immune microenvironment (TIME), ultimately resulting in resistance to immunotherapy. Here, we aim to identify a critical oncogenic pathway involved in an antigen-expressing c-MYC-lucOSOE/Tp53KO hepatocellular carcinoma (HCC) mouse model that simulates immune response against tumour-associated antigens.

1 A runner’s body can be any shape, but they’re often lean with toned legs. Anyone who runs has a runner’s body. And because people naturally come in all different shapes and sizes, there’s no one way for a runner’s body to look! While your genetics primarily determine the shape and size of your body, Tucker explains that runners can share similar characteristics.

Download Article The miles you need for weight loss, longevity, mental health & more Download Article Running is an easy and enjoyable way to stay in shape—just throw on your shoes and hit the pavement! How many miles a day should you be running, though? In this article, we’ll explain the recommended daily mileage for beginning, intermediate, and advanced runners, plus how to get started with running and increase your mileage and endurance safely.