Kalthoum Ben M'barek on Muck Rack

Kalthoum Ben M'barek

As seen in: Cell Press
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Articles

Perilipin membrane-integration determines Lipid Droplet heterogeneity in differentiating adipocytes

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By Mario Majchrzak, Ozren Stojanovic, Dalila Ajjaji, Kalthoum Ben M'barek
| biorxiv.org
Abstract The storage of fat within lipid droplets (LDs) of adipocytes is critical for whole-body health. Acute fatty acid (FA) uptake by differentiating adipocytes leads to the formation of at least two LD-classes marked by distinct perilipins (PLINs). How this LD-heterogeneity arises is an important yet unresolved cell biological problem.
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Perilipin membrane association determines Lipid Droplet heterogeneity in differentiating adipocytes

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By Dalila Ajjaji, Kalthoum Ben M'barek, Mario Majchrzak, Ozren Stojanovic
| biorxiv.org
Abstract The storage of fat within lipid droplets (LDs) of adipocytes is critical for whole-body health. Acute fatty acid uptake by adipocytes leads to the formation of at least two LD-classes marked by distinct members of the perilipin (PLIN) protein-family. How LD-heterogeneity arises is an important yet unresolved cell biological problem.
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ER Membrane Phospholipids and Surface Tension Control Cellular Lipid Droplet Formation

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By École Normale Supérieure, Université Paris Diderot, Kalthoum Ben M'barek
| Cell Press Verified
Figure 1Lipids, Not Coat Proteins, Can Physically Mediate LD Budding(A) Illustration of lipid droplet (LD) budding step. The contribution of proteins and lipids on LD budding is unknown.(B) Surface tension values of LDs purified from mammalian (Cos 7) and Drosophila (Kc167) cells ( Figure S1 ). Error bars represent the SD.(C) Reconstitution of the LD formation topology in the ER.
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