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Kareem N. Mohni on Muck Rack

Kareem N. Mohni

As seen in: Cell Press
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Articles

Functional Analysis of the Replication Fork Proteome Identifies BET Proteins as PCNA Regulators

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By Sarah R. Wessel, Kareem N. Mohni, Jessica W. Luzwick, Huzefa Dungrawala
| Cell Press Verified
Highlights • iPOND proteomics identifies 593 proteins enriched on nascent DNA • 101 proteins are found to be depleted from nascent DNA compared to bulk chromatin • Loss-of-function and bioinformatics analyses provide functional validation • The BET proteins BRD2, BRD3, and BRD4 bind ATAD5 and regulate PCNA unloading Summary Identifying proteins that function at replication forks is essential to understanding DNA replication, chromatin assembly, and replication-coupled DNA repair mechanisms.
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Cell Press: Cell Press

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By Kareem N. Mohni, Sarah R. Wessel, Brandt Eichman, Kavi Mehta, David Cortez, Runxiang Zhao, Andrea C. Wojciechowski, Jessica W. Luzwick, Hillary Layden, Petria S. Thompson
| Cell Press Verified
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By Dmitri A. Petrov, Dianne I. Lou, Eui Tae Kim, Nicholas R. Meyerson, Neha J. Pancholi, Kareem N. Mohni, David Enard, Sandra K. Weller, Matthew D. Weitzman, Sara L. Sawyer
| secure.jbs.elsevierhealth.com
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