Karina Sharma on Muck Rack

Karina Sharma

College Park, Dubai
As seen in: Nature, National Geographic Traveler, MDPI, Vogue Arabia, Vogue Man Arabia, Modern Luxury Angeleno, Addison County Independent, News 24
Maryland • Dubai • UMD'18

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Articles

Epigenetic memory of colitis promotes tumour growth

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By Surya Nagaraja, Lety Ojeda-Miron, Ruochi Zhang, Ena Oreskovic, Conrad Hock, Yan Hu, Daniel Zeve, Karina Sharma, Roni R. Hyman, Qiming Zhang, David Breault, Omer Yilmaz, Ömer H. Yilmaz, Jason D. Buenrostro
| Nature Verified
Abstract Chronic inflammation is a well-established risk factor for cancer, but the underlying molecular mechanisms remain unclear1,2. Using a mouse model of colitis, we demonstrate that colonic stem cells retain an epigenetic memory of inflammation following disease resolution that persists for more than 100 days. Here we find that memory of colitis is characterized by a cumulative gain of activator protein 1 (AP-1) transcription factor activity, with durable changes to chromatin accessibility.
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Unlock Success: 5 Habits All High Achievers Swear By

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By Karina Sharma
| News 24 Verified
They know exactly what they want. High achievers set specific, actionable goals.
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12 Times Queen Rania and King Abdullah II Made Us Believe in Love Again

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By Karina Sharma
| Vogue Arabia Verified
It all started at a dinner party back in 1992. Queen Rania met the then-Prince of Jordan, Abdullah II bin Al-Hussein, at a dinner party and the rest, as they say, was history. The iconic duo was married the following year on June 10 for a summer wedding the Arab world will never forget.
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