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Enhanced Clearance of HIV‐1 Broadly Neutralizing Antibody VRC07‐523‐LS During Viremia: Influences on Trial Design and Analysis
1 Introduction Between acute and chronic HIV-1 infection, endogenous antibodies dynamically shift in immunoglobulin type and target epitope over the first 3 months [1, 2]. After 2–4 years of natural infection, 10%–30% of individuals develop potent and cross-reactive anti-HIV-1 broadly neutralizing antibodies (BNAbs) that are capable of neutralizing heterologous viral subtypes [3-6].
Author Correction: High monoclonal neutralization titers reduced breakthrough HIV-1 viral loads in the Antibody Mediated Prevention trials - Nature Communications
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Correction to: Nature Communications https://doi.org/10.1038/s41467-023-43384-y, published online 14 December 2023 The originally published version of this Article contained several errors in references to previous work.
By Daniel Reeves, Bryan Mayer, Allan C. deCamp, Yunda Huang, Bo Zhang, Lindsay N. Carpp, Craig A Magaret, Michal Juraska, Peter Gilbert, David C. Montefiori, Katharine J. Bar, E. Fabian Cardozo-Ojeda, Joshua T Schiffer, Paul T. Edlefsen, Lynn Morris, Carolyn Williamson, Kelly E. Seaton, Georgia Tomaras, Lawrence Corey, Paul A Goepfert, Martín Casapía, Shelly Karuna
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Development of screening assays for use of broadly neutralizing antibodies in people with HIV
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