Katherine Cahill

Supported by the United Kingdom and (investigator-led grants [to I.M.A.]). Disclosure of potential conflict of interest: I. M. Adcock has received grants from GSK and Sanofi outside the scope of this article. T. T. Hansel has shares in Mucosal Diagnostics, an Imperial College spinoff company and has received royalty payments from Hunt Developments (UK), Ltd, Midhurst, West Sussex. The remaining author declares no

Asthma and lower airway disease Early-preschool wheeze trajectories are predominantly nonallergic with distinct biologic and microbiome traits Section snippets Study design and participants The CHILD Cohort Study is a prospective longitudinal birth cohort study.18 Between 2008 and 2012, a total of 3621 pregnant women with eligible infants (N = 3455) who had no congenital abnormalities and were born at a minimum of 34 weeks of gestation were enrolled from 4 Canadian cities (Vancouver,...

Section snippets Methods A detailed account of the Methods used in this study is included in this article’s Online Repository (available at www.jacionline.org). Clinical description The highlights of the patients' clinical picture have been mentioned in Table I. A detailed account of their clinical history is included in this article’s Online Repository (available at www.jacionline.org).