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Katherine Lawler on Muck Rack

Katherine Lawler

As seen in: Nature, PLOS Biology, BMJ Open, MDPI, Science Magazine, BioRxiv, Cell Press, CSIRO Publishing, WARC, The Canadian Journal of Human Sexuality ( UTP) and
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Articles

A Hormone Cell Atlas maps the human endocrine system at cellular resolution

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By Oliver Lindecke, Maria Bue, Marion Clavel, Lijiang Fei, Isabel Huang-Doran, Katherine Lawler, Yizhou Yu, Jan Patrick Pett, Dinesh O. Shah, Jaume Margalef-Rieres, Joseph S. Pohlman, Batuhan Cakir, Madelyn Moy, Robert Legg, Chuan Xu, Ken To, Duy Vu Pham, Duy Phạm, Alexander Predeus, Ruth Hanssen, Tessa M. Cacciottolo, Rakesh Kapuge, Krzysztof Polanski, Amanda Oliver, Sarah A Teichmann, I. Sadaf Farooqi
| Science Magazine Verified
Abstract Supplementary Materials References and Notes Information & Authors Metrics & Citations Check Access References Figures Tables Media Share Abstract Hormones act across tissues and organs to coordinate physiological functions. Drawing inspiration from the Human Cell Atlas, we analyzed expression of 379 hormone and receptor genes in a transcriptomic dataset comprising 14 million single cells and nuclei across 47 human tissues.
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Structures of human PTP1B variants reveal allosteric sites to target for weight loss therapy

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By Aliki Perdikari, Virgil A Woods, Ali Ebrahim, Katherine Lawler
| BioRxiv
Abstract Protein Tyrosine Phosphatase 1B (PTP1B) is a negative regulator of leptin signaling whose disruption protects against diet-induced obesity in mice. We investigated whether structural characterization of human PTP1B variant proteins might reveal allosteric sites to target for weight loss therapy. To do so, we selected 12 rare variants for functional characterization from exomes from 997 people with persistent thinness and 200,000 people from UK Biobank.
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Factors influencing participation in clinical supervision: a qualitative study reflecting physiotherapist and manager perspectives

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By Nicholas Taylor, Katherine Lawler, Kimberley Williams, Sarah Osiurak
| CSIRO Publishing Verified
Journal of the Australian Healthcare & Hospitals Association You are here: Home > Journals > AH > AH24293 RESEARCH ARTICLE Previous Next Contents Vol 49(1) Sarah Osiurak A , Nicholas F. Taylor B C , Katherine Lawler B C , Kimberley Williams A , Timothy Albiston A and David A. Snowdon C D * + Author Affiliations - Author Affiliations A Physiotherapy Department, Eastern Health, Box Hill, Vic, Australia. B Allied Health Clinical Research Office, Eastern Health, Box Hill, Vic, Australia.
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