Katie Lee on Muck Rack

Katie Lee

As seen in: Good Housekeeping, Medium, Wiley Online Library, Cambridge University Press & Assessment, GlobeNewswire, StreetInsider, EIN News, Buffalo News, Lexology, medRxiv, The Journal of Clinical Investigation and
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Articles

Uncoupling TGFβ1 signalling from collagen protein synthesis in Dupuytren's disease

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By Gabriella E Cooper, Sahem M Alkharabsheh, Katie Lee, Jade A Gumbs
| Wiley Online Library Verified
Introduction Dupuytren's disease is a progressive fibroproliferative condition of the palmar fascia (PF) (aponeurosis) of the hand that can result in debilitating digital contractures [1, 2]. Following the formation of highly cellular ‘nodules’, collagenous cords align along the length of the fascia form and contract due to myofibroblast activity [3]. Progression is staged from 0 to IV depending on the degree of digit contracture [4].
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Active synthesis of type I collagen homotrimer in Dupuytren’s fibrosis is unaffected by anti–TNF-α treatment

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By JCI Insight, Kate Williamson, Katie Lee, Emma Beamish
| The Journal of Clinical Investigation
Abstract Dupuytren’s disease is a common fibroproliferative disease of the palmar fascia of the hand, with advanced cases treated surgically. Anti-TNF injection has undergone phase 2 trials and may be effective in slowing early-stage disease progression. Here we sought to determine how new synthesis of type I collagen in Dupuytren’s differs from normal palmar fascia samples and to analyze the role of TNF in aberrant collagen synthesis.
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A tissue multiplexing approach to maximise spatial transcriptomics output from precious pathology specimens

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By Yung-Ching Kao, Katie Lee, Chenhao Zhou, Andrew Causer
| medRxiv
: HPS is a shareholder of MoleMap NZ Limited and e-derm consult GmbH, and undertakes regular teledermatological reporting for both companies. HPS provides medical consultant services for Canfield Scientific Inc. and First Derm by iDoc24 Inc The other authors have no conflicts of interest to disclose.
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