Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile
Articles by Ke Ning
Ginsenoside Rb1 alleviates uterine aging via AMPK-mediated mTOR inactivation
Abstract Uterine aging impairs fertility and reproductive health, but the underlying pathogenic mechanisms and effective treatment strategies remain elusive. Defective endometrial decidualization and implantation failure are hallmarks of uterine aging, which can be driven by cellular senescence, especially in endometrial stromal cells (EnSCs). Rb1 has been reported to relieve cellular senescence by suppressing oxidative and inflammatory pathways.
Life cycle carbon emission accounting and emission reduction potential assessment of container and domestic glass industry in China
?Mathematical formulae have been encoded as MathML and are displayed in this HTML version using MathJax in order to improve their display. Uncheck the box to turn MathJax off. This feature requires Javascript. Click on a formula to zoom. Abstract The container and domestic glass (CDG) industry is one of the most energy-intensive sectors in China.
Immuno-metabolic crosstalk in osteoarthritis: from mechanisms to therapies
Abstract Background: Osteoarthritis (OA) is a heterogeneous whole-joint disorder influenced by mechanical stress, aging, previous trauma, genetic susceptibility, subchonrral bone alterations, and localized inflamation.Emerging evidence suggests that immune and metabolic processes alterations may be involved in OA pathogenesis particularly in inflammatory and metabolically dysregulated subtypes.
Overexpression of miR-144-3p inhibits the expression of NLRP3 in fibroblast-like synoviocytes of osteoarthritis
Abstract To investigate whether overexpression of miR-144-3p can inhibit the activation of the NLRP3 inflammasome and the release of associated inflammatory factors in osteoarthritis. In this study, human FLS were stimulated by LPS to establish an in vitro inflammatory model, and transfected with miR-144-3p mimic, inhibitor and their corresponding negative control. The mRNA and protein expressions of NLRP3 inflammasome related molecules were detected by RT-qPCR and Western blot.
EHMT2 aggravates vascular remodeling via epigenetic inhibition of GADD45G
Abstract Euchromatic histone-lysine N-methyltransferase 2 (EHMT2) has been implicated in cardiovascular diseases, yet its role in vascular remodeling remains incompletely understood. Here we investigated the contribution of EHMT2 to vascular smooth muscle cell (VSMC) proliferation, migration and neointima formation following vascular injury using carotid artery injury models and in vitro VSMC studies.
Reliability‐Based Optimization Design with Interval Parameters for Reducing Yaw Braking Noise
References 1. Analysis of disc brake squeal using finite element methods. SAE Transactions 1989; 98(6): 1138–1146. 2, . Suppression of brake squeal noise applying a finite element brake and pad model enhanced by spectral-based assurance criteria. Applied Acoustics 2008; 69(3): 196–214. 3, , , , . Numerical investigation of material properties and operating parameters effects in generating motorcycle brake squeal using the finite element method.
Non-destructive in situ monitoring of structural changes of 3D tumor spheroids during the formation, migration, and fusion process
eLife Assessment The ingenious design in this study achieved the observation of 3D cell spheroids from an additional lateral view and gained more comprehensive information than the traditional one angle of imaging. This extended the methods to investigate cell behaviors in the growth or migration of tumor organoids in a time-lapse manner and these extensions should be important to the field. The authors provide compelling evidence that the methods work as described.
Notoginsenoside R1 Attenuates H/R Injury in H9c2 Cells by Maintaining Mitochondrial Homeostasis
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
dCasMINI-mediated therapy rescues photoreceptors degeneration in a mouse model of retinitis pigmentosa
Published In Science Advances Volume 10 | Issue 51 December 2024 Article versions Submission history Received: 5 January 2024 Accepted: 13 November 2024 Permissions Request permissions for this article. Acknowledgments We thank B. A. Tucker of University of lowa for providing the human PDE6B constructs. In addition, we extend our thanks to F. Wang (University of California San Francisco) for the assistance in the study of looming-induced escape behavior.
2024 International Symposium on New Materials Interdisciplinary Frontiers convened
NEXT The 2024 International Symposium on New Materials Interdisciplinary Frontiers was held in Wuhan from November 1 to 4. The conference was co-organized by the School of Materials Science and Engineering and the Office of International Affairs of Huazhong University of Science and Technology.
Myokines May Be the Answer to the Beneficial Immunomodulation of Tailored Exercise-A Narrative Review
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Unraveling the Mechanisms of S100A8/A9 in Myocardial Injury and Dysfunction
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Non-destructive in situ monitoring of structural changes of 3D tumor spheroids during the formation, migration, and fusion process
Abstract For traditional laboratory microscopy observation, the multi-dimensional, real-time, in situ observation of three-dimensional (3D) cell spheroids has always been the pain point in cell spheroid observation. In this study, we designed a side-view observation petri dish/device that reflects light, enabling in situ observation of the 3D morphology of cell spheroids using conventional inverted laboratory microscopes.
Post-traumatic stress, depression, and anxiety during the 2021 Myanmar conflict: a nationwide population-based survey
Research in context In 2021, the UN had warned about Myanmar facing the ‘triple crises’ of mass conflict, uncontrolled COVID-19, and economic collapse. Given that each crisis could have a substantial mental health impact, the ‘triple crises’ in Myanmar could jointly exert an even more devastating toll on the population mental health.
KLF transcription factors in bone diseases
1 INTRODUCTION The Krüppel-like factor (KLF) family of transcription factors, which means ‘cripple’ in German, is a family of regulators essential for DNA-binding transcription.
High throughput generating stable spheroids with tip‐refill wafer
CONFLICT OF INTEREST STATEMENT There are no conflicts to declare. Supporting Information Filename Description biot202300427-sup-0001-SuppMat.docx3.4 MB Supporting Information biot202300427-sup-0002-VideoS1.avi2.3 MB Supporting Information biot202300427-sup-0003-VideoS2.avi61.9 MB Supporting Information biot202300427-sup-0004-VideoS3.avi4.1 MB Supporting Information biot202300427-sup-0005-VideoS4.avi79 MB Supporting Information REFERENCES 1, , , , & (2018).
Compartmentalized ciliation changes of oligodendrocytes in aged mouse optic nerve
CONFLICT OF INTEREST STATEMENT The authors declare no financial/non-financial competing interest. Supporting Information Filename Description jnr25273-sup-0001-FigureS1.tifTIFF image, 2.2 MB FIGURE S1 Comparison of primary cilia profile of visual pathway in young and aged C57BL/6 mice. Quantification of ciliation and ciliary length of Olig2-positive oligodendrocytes in optic nerves in each region.
Label-Free and Real-Time Optical Detection of Affinity Binding of the Antibody on Adherent Live Cells
Download Hi-Res ImageDownload to MS-PowerPointCite This:Anal. Chem. 2024, XXXX, XXX Terms & Conditions Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may be downloaded by article for research use (if there is a public use license linked to the relevant article, that license may permit other uses).
Recapitulating the Drifting and Fusion of Two-Generation Spheroids on Concave Agarose Microwells
1. Introduction In the field of cellular biology, organizing cells into three-dimensional (3D) structures has become a powerful tool for studying cellular behavior in more realistic and complex settings [1,2,3,4,5]. The creation of 3D cell culture systems has allowed researchers to investigate the development, differentiation, proliferation, migration of cells, and interactions between cells and extracellular matrix components [6,7,8,9,10].
Protective Effects of Different Molecular Weights of Purslane (Portulaca oleracea L.) Aqueous Extract on DSS-Induced Ulcerative Colitis in Mice
Open AccessArticle by Ke Ning 1, Yameng Duan 1, Weiwei Tong 1, Yue Chen 1, Qinghui Zhang 1, Qiuhong Xie 1,2,* and Hongyu Xiang 1,2,* 1 Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education, School of Life Sciences, Jilin University, Changchun 130012, China 2 Institute of Changbai Mountain Resource and Health, Jilin University, Fusong 134504, China * Authors to whom correspondence should be addressed.
Sustainability | Free Full-Text | The Effects of the Exercise Intervention on Fundamental Movement Skills in Children with Attention Deficit Hyperactivity Disorder and/or Autism Spectrum Disorder: A Meta-Analysis
Open AccessReview by Yue Ye 1, Ke Ning 1,2,*, Bingjun Wan 1,2 and Chunzi Shangguan 1 1 School of Physical Education, Shaanxi Normal University, Xi’an 710119, China 2 Shaanxi Children and Youth Sports Research Center, Xi’an 710119, China * Author to whom correspondence should be addressed.
COVID-19 Vaccination Willingness and Reasons for Vaccine Refusal
Key Points Question What were the reasons for COVID-19 vaccine refusal in Hong Kong, and what policy measures may be associated with higher vaccine uptake? Findings This cohort study used data from 28 007 interviews over 20 waves, including 1114 participants in the latest wave in 2022, found that 75.0% of vaccine refusal could be attributable to mistrust in health authorities, low vaccine confidence, misconceptions, and political views.
The association between early life mental health and alcohol use behaviours in adulthood: A systematic review
Loading metrics Open Access Peer-reviewed Research Article Ke Ning , Dawid Gondek, Praveetha Patalay, George B. Ploubidis Ke Ning, Dawid Gondek, Praveetha Patalay, George B. Ploubidis Published: February 18, 2020 https://doi.org/10.1371/journal.pone.0228667 Figures Abstract This systematic review aims to summarise current evidence on the association between early life mental health and alcohol use behaviours in adulthood.
Ectodysplasin A protein promotes corneal epithelial cell proliferation
The EDA gene encodes ectodysplasin A (Eda), which if mutated causes X-linked hypohidrotic ectodermal dysplasia (XLHED) disease in humans. Ocular surface changes occur in XLHED patients whereas its underlying mechanism remains elusive. In this study, we found Eda was highly expressed in meibomian glands, and it was detected in human tears but not serum. Corneal epithelial integrity was defective and the thickness was reduced in the early postnatal stage of Eda mutant Tabby mice.
Show More
loading
Actions
Is this you?
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Get in touch with Ke
Contact Ke, search articles and posts on X, monitor coverage, and track replies from one place.
Learn more about Muck Rack