CONFLICT OF INTEREST STATEMENT K. A. Clark, M. A. Elliott, C. M. O'Donnell, S. Tauhid, R. Chu, S. Khalil, P. Sati, A. DuVal, N. Pellegrini, and J. Zurawski have received research support from Novartis and I-Mab Biopharma. B. E. Dewey is supported by a postdoctoral fellowship from the National Multiple Sclerosis Society. C. Markowitz has received consulting fees from Alexion, Bayer Healthcare, Biogen, BMS/Celgene, Janssen/Actelion, EMD Serono, Novartis, Roche/Genentech, and Sanofi/Genzyme. A.