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Articles by Ken To
Spatially resolved multiomics of human meningeal development reveal lineage and disease dynamics
Abstract The meninges are increasingly recognized as key stromal and immune niches supporting cranial development. Here we constructed a paired single-nuclei RNA and Assay for Transposase-Accessible Chromatin atlas of human meningeal development from 6 to 21 postconception weeks across cranial regions. By integrating spatial transcriptomics, we resolved cell types across meningeal layers.
A Hormone Cell Atlas maps the human endocrine system at cellular resolution
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Abstract Supplementary Materials References and Notes Information & Authors Metrics & Citations Check Access References Figures Tables Media Share Abstract Hormones act across tissues and organs to coordinate physiological functions. Drawing inspiration from the Human Cell Atlas, we analyzed expression of 379 hormone and receptor genes in a transcriptomic dataset comprising 14 million single cells and nuclei across 47 human tissues.
By Oliver Lindecke, Maria Bue, Marion Clavel, Lijiang Fei, Isabel Huang-Doran, Katherine Lawler, Yizhou Yu, Jan Patrick Pett, Dinesh O. Shah, Jaume Margalef-Rieres, Joseph S. Pohlman, Batuhan Cakir, Madelyn Moy, Robert Legg, Chuan Xu, Ken To, Duy Vu Pham, Duy Phạm, Alexander Predeus, Ruth Hanssen, Tessa M. Cacciottolo, Rakesh Kapuge, Krzysztof Polanski, Amanda Oliver, Sarah A Teichmann, I. Sadaf Farooqi
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Mindsets Matter: A Mediation Analysis of the Role of a Technological Growth Mindset in Generative Artificial Intelligence Usage in Higher Education
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Development of the hormone cell atlas
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | ISSN 1479-6848 (online) Search Issues/Conferences Cite About Our Services Policies Contact Disclaimer SFEBES2025 Oral Communications Metabolism, Obesity and Diabetes (6 abstracts) Development of the hormone cell atlas Hormones are secreted by diverse cell types across endocrine and non-endocrine tissues, acting via cognate receptors to coordinate cellular responses.
A multiomic atlas of human early skeletal development
Abstract Bone and joint formation in the developing skeleton rely on co-ordinated differentiation of progenitors in the nascent developing limbs and joints. The cell states, epigenetic processes and key regulatory factors underlying their lineage commitment to osteogenic and other mesenchymal populations during ossification and joint formation remain poorly understood and are largely unexplored in human studies.
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