Psilocybin mushrooms contain numerous chemical compounds that researchers have not yet studied. (Smitt/iStock via Getty Images Plus) Amid a renaissance in the science of psychedelics, public interest in psilocybin — or magic mushrooms, as they’ve long been known — is surging. One study found that rates of psilocybin use increased 44% among adults ages 18-29 from 2019 to 2023, and 188% among those over age 30. This amounts to more than 5 million adults using psilocybin in 2023 alone.