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Kevin Choi

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Articles

Structural energetics of cold sensitivity

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By Kevin Choi, Xiaoxuan Lin, Yifan Cheng, David Julius
| Nature Verified
Abstract Thermosensitive transient receptor potential (TRP) ion channels enable somatosensory nerve fibres to detect changes in our thermal environment over a wide physiologic range1,2,3. In mammals, the menthol receptor, TRPM8, is activated by temperatures below approximately 26 °C and is essential for the perception of cold or chemical cooling agents4,5,6.
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The structural basis of cold sensitivity

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By Kevin Choi, Xiaoxuan Lin, Yifan Cheng, David Julius
| BioRxiv
Abstract Thermosensitive TRP ion channels enable somatosensory nerve fibers to detect changes in our thermal environment over a wide physiologic range. In mammals, the menthol receptor, TRPM8, is activated by temperatures below ~26°C and is essential for the perception of cold or chemical cooling agents. A fascinating, yet still unachieved goal is to elucidate structural mechanisms whereby TRPM8 or other thermosensitive channels are gated by changes in ambient temperature.
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Clinical outcomes of peroral endoscopic myotomy with and without septotomy for management of epiphrenic diverticula - an international multicenter experience - Gastrointestinal Endoscopy

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By Apurva Shrigiriwar, Shruti Mony, Farimah Fayyaz, Manabu Onimaru, Marc Monachese, Linda Zhang, Felix Corre, Kevin Choi, Ashish Gandhi, Divya Chalikonda, Margaret Keane, Bachir Ghandour, Padmini Azmeera, Hoover Wu, Jose Villamarin-Cor
| Gastrointestinal Endoscopy Verified
This paper is only available as a PDF. To read, Please Download here.
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