Kevin Hay on Muck Rack

Kevin Hay

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  • Journalist, BBC
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Articles

GPNMB-directed CAR T cell therapy against MiT/TFE-family fusion-driven solid tumors

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By Franz J. Zemp, Hyojin Song, Taye Louie, Hongrui Liu, Yeon Ok Suh, Edna Ayerim Mandujano-Tinoco, Nicolas Collao, Joanna Pyczek, Kristofor K. Ellestad, Cini M. John, Laura K. Mah, Jahanara Rajwani, Danyel Evseev, Madison Turk, Sacha Benaoudia, Jonathan Alex, Victor Naumenko, Varsha Thoppey Manoharan, Harmony Smith, Aaron Gillmor, Hayley M. Todesco, Bo-Young Ahn, Colleen Anderson, Saif Sikdar, Tarek A. Bismar, Daniel Heng, Keith Lawson, W. Marston Linehan, Haley Pedersen, Paul Gordon, John McIntyre Verified, john Mcintyre, John MacGregor, Livia Garzia, Kathy Brodeur-Robb, Travis Ogilvie, Patrick Schöffski, Agnieszka Wozniak, Robert Holt, John Bell, Donna L. Senger, Victor A Lewis, Michael J. Monument, Omar Khan, Lou Baudrier, Pierre Billon, Vincent Gabriel, Jeff Biernaskie, Kiril Trpkov, Kevin Hay Verified, Jennifer Chan, Ramy R. Saleh, Jan Henning, Mona Shafey, A. Sorana Morrissy, Douglas J. Mahoney, Zackariah Breckenridge, Gurveer S. Gill, Kiran Narta, Louisa Guignard, Jada Curry, Jethro Langley, Mobina Kazemi Mehrabadi, Geneece N. Y. Gilbert, Ted B. Verhey, Katalin Osz, Ana Bogossian, Shahrbano Rukunuddin, Lisa DiFrancesco, Kyle Potts, Jennifer Quizi, Nicole L. Prokopishyn
| Nature Verified
Abstract Chimeric antigen receptor (CAR) T cell therapy for solid tumors is constrained by the scarcity of safe, uniformly expressed cell-surface targets. Here we identify glycoprotein NMB (GPNMB)—an MiT/TFE-family fusion-driven protein—as being highly, homogeneously and stably expressed in primary and relapsed alveolar soft-part sarcoma (ASPS) and translocation renal cell carcinoma.
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How to Be Courageous and Compassionate at Work

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By Kevin Hay Verified
| The Aquila Report Verified
The times we live in may grow more hostile. The cost of faithfulness may increase. But the opportunity for witness is greater than ever. Christ is still building His church, and no cultural opposition can stop Him. So let’s be Christians who navigate our workplaces with truth that will not bend and love that will not fail. For Christians today, the workplace is one of the clearest testing grounds for our faith.
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How the Gospel Shapes Our Schedules

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By Kevin Hay Verified
| The Aquila Report Verified
The lesson is not that work doesn’t matter. Meals need to be made, jobs need to be done, and responsibilities must be carried out. The lesson is that eternal things must always take priority over urgent things. Sitting at the feet of Jesus will never feel urgent, but it is always essential. When we choose urgent over eternal, we are essentially saying that what shouts the loudest deserves our time. But when we prioritize the eternal, we are saying that Christ deserves our best attention all the time.
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