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Keziah Hernandez on Muck Rack

Keziah Hernandez

As seen in: Nature
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A single-nucleus multiomic high-resolution atlas of the Mus musculus spleen

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By Aliza B Rubenstein, Sindhu Vangeti, Aarti Tripathi, Gabriel Laghlali, Seok-Chan Park, Mital Vasoya, Minghui Lu, Mary Anne S. Amper, Tarani Kanta Barman, Shailendra Chauhan, Venugopalan D. Nair, Alexander Bukreyev, Michael Schotsaert, Adolfo Garcia-Sastre, Stuart C. Sealfon, Irene Ramos, Elena Zaslavsky, Nima Assad, Keziah Hernandez
| Nature Verified
Abstract The spleen is a central organ for systemic immune surveillance and is especially important in mouse models to study infection, vaccination, and inflammatory disease. However, a high-resolution single cell reference for the murine spleen has been lacking. Here we present a single-nucleus multiomic atlas using same-cell single-nucleus RNA-seq and single-nucleus ATAC-seq profiling of 12 adult C57BL/6 mouse spleen samples.
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